PIXABAY, GERALTThe creation of optogenetics as a popular approach to manipulating neural behavior is largely attributed to Stanford University’s Karl Deisseroth and MIT’s Ed Boyden. The pair, in collaboration with their colleagues, published a seminal Nature Neuroscience paper (cited more than 2,100 times, according to Google Scholar) in 2005 that is often credited as the beginning of optogenetics.
But a report in STAT News today (September 1) reveals that a Wayne State researcher by the name of Zhuo-Hua Pan actually got optogenetics to work first.
The method works by introducing channelrhodopsin into cells; activating the light-sensitive molecule alters the activity of the cell. “In August 2004, Boyden shined light on a brain neuron in a dish and recorded electrical activity from the channelrhodopsin,” STAT reported. “Pan had done the same thing with retina neurons six months earlier. But then he got scooped.”
Pan presented his work at a conference in 2005, a few months before Boyden and Deisseroth published their paper. But Pan struggled to get his work published in a journal until a year later. (Read Boyden’s account of the history of ...
