Tide Shifting on Embryo Gene Editing?

An international bioethics group says that research that involves editing genes in human embryos can be valuable, though it doesn’t approve of making “designer babies.”

Written byBob Grant
| 2 min read

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A human embryo at seven weeksWIKIMEDIA, OPENSTAX COLLEGEEver since researchers in China published a Protein & Cell paper this April detailing their use of CRISPR/Cas9 gene editing in early human embryos, a debate over the bioethics of such work has been raging. The National Institutes of Health (NIH) quickly issued a statement indicating that it would not fund such research in humans, but some life scientists disagreed.

Now the Hinxton Group—an international consortium of stem-cell researchers, policy wonks, and bioethicists—has come out in favor of research that involves using CRISPR/Cas9 to edit genes in human embryos but not for the creation of designer offspring. “We all agreed that while this technology has tremendous value to basic research and enormous potential for somatic clinical uses, it is not sufficiently developed to consider human genome editing for clinical reproductive purposes at this time,” the group said in a statement released yesterday (September 9). “Genome editing has tremendous value as a tool to address fundamental questions of human and non-human animal biology and their similarities and differences.”

The Hinxton Group’s position is more or less aligned with that of Emmanuelle Charpentier of Germany’s Helmholtz Centre ...

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  • From 2017 to 2022, Bob Grant was Editor in Chief of The Scientist, where he started in 2007 as a Staff Writer. Before joining the team, he worked as a reporter at Audubon and earned a master’s degree in science journalism from New York University. In his previous life, he pursued a career in science, getting a bachelor’s degree in wildlife biology from Montana State University and a master’s degree in marine biology from the College of Charleston in South Carolina. Bob edited Reading Frames and other sections of the magazine.

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