A corn snake against a black background. Comparative genomics and CRISPR-Cas9 helped identify the genes that give it its characteristic dorsal blotches.
| 4 min read
Comparing the genomes of snakes with distinct coloration patterns pinpointed the genetic variants that contribute to these intricate designs.

CRISPR/Cas

A CRISPR-Cas platform uses microfluidic droplets, encasing CRISPR components and DNA barcodes, and injects individual droplets into zebrafish embryos. The embryos are raised and then researchers link phenotypes to genotypes by sequencing the barcodes.

DNA Droplets in Motion Accelerate Gene Discovery

Graphic showing Cas9 introducing blunt end double-strand breaks in DNA while Cas12a introduces staggered cuts in the DNA.

What’s the Difference Between Cas9 and Cas12a Nucleases?

istock

Reaching New Heights with Genetic Engineering Techniques

Image of Brussels sprouts and endives on a wooden background.

Greens and Genes: The Bitter Truth Behind Your Veggie Preferences

An illustration of a perforated grey nucleus holding colorful spaghetti-like DNA strands.

Gene Proximity to Nuclear Speckles Drives Efficient mRNA Splicing

Lonza

Lonza and Vertex Sign a Long-Term Commercial Supply Agreement for CASGEVY® (exagamglogene autotemcel)

A conceptual illustration of scissors, which represents a CRISPR-Cas9 complex, cutting a DNA molecule.

Cell Engineering 101: Editing with CRISPR

Two cells on a purple background. Two mechanisms of gene silencing are shown in the cell on the left, while a double-strand break in a DNA region is shown in the cell on the right.

What’s the Difference Between Gene Knockdown and Gene Knockout?

Neurons in culture

Lighting Up the Neuronal Cytoskeleton

Trending

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

An illustration of an in vitro fertilized embryo, which researchers recently used to study maternal aneuploidy

Genetic Basis of Aneuploidy, Which Often Causes Pregnancy Loss, Revealed

Illustration of a hole in the shape of a dollar sign on a blue background. One character is falling into the hole at the bottom of the “S” while another individual is holding another up at the top of the “S”. The image represents the absence of funding for researchers in biotech with the cancellation of the SBIR/STTR program.

The Federal Government’s Research Innovation Lifeline Has Gone Dark

A mouse aorta with immunofluorescence tagging of various molecules, emphasizing the close connection between vasculature and fat.

How Fat Type Shapes Hypertension Risk

Multimedia

Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

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Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

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Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

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Sino Biological's Launch of SwiftFluo® TR-FRET Kits Pioneers a New Era in High-Throughout Kinase Inhibitor Screening

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SPT Labtech enables automated Twist Bioscience NGS library preparation workflows on SPT's firefly platform

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Nuclera eProtein Discovery System installed at leading Universities in Taiwan

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BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control