Base Editors Cause Off-Target Mutations in RNA
Base Editors Cause Off-Target Mutations in RNA
A new study indicates that the modified CRISPR-Cas9 technology will need to be further refined before it can safely be used for research and therapeutic applications.
Base Editors Cause Off-Target Mutations in RNA
Base Editors Cause Off-Target Mutations in RNA

A new study indicates that the modified CRISPR-Cas9 technology will need to be further refined before it can safely be used for research and therapeutic applications.

A new study indicates that the modified CRISPR-Cas9 technology will need to be further refined before it can safely be used for research and therapeutic applications.

CRISPR/Cas
Two Patients Treated with CRISPRed Cells in Immunotherapy Trial
Two Patients Treated with CRISPRed Cells in Immunotherapy Trial
Shawna Williams | Apr 16, 2019
One person with multiple myeloma and one with sarcoma are the first so far to receive the genetically engineered T cells in the study.
Image of the Day: An Infectious Glow
Image of the Day: An Infectious Glow
Carolyn Wilke | Mar 7, 2019
In CRISPRed fruit flies that lack certain antimicrobial peptides, bacterial infections flourish, as revealed by fluorescent markers.
Better Base Editing in Plants
Better Base Editing in Plants
Ruth Williams | Feb 1, 2019
Adenine editing enzymes have been adapted for use in plants.
Infographic: Plant Genome Editors Get A New Tool
Infographic: Plant Genome Editors Get A New Tool
Ruth Williams | Feb 1, 2019
Adenine editing enzymes have been adapted for use in plants.
Clones Made of CRISPRed Monkeys
Clones Made of CRISPRed Monkeys
Carolyn Wilke | Jan 25, 2019
Researchers edited macaque embryos to induce symptoms of sleep disorders and chose one animal to clone. A bioethicist questions the study’s appropriateness.
First Successful Gene Drive in Mammals
First Successful Gene Drive in Mammals
Abby Olena | Jan 23, 2019
Researchers use a CRISPR-Cas9 strategy to expand a desired trait from 50 percent of mouse pups to about 72 percent.
Taming the Transposon Hordes
Taming the Transposon Hordes
Ruth Williams | Jan 1, 2019
Researchers repurpose the CRISPR machinery to turn whole classes of transposable elements on or off.
Photos of the Year
Photos of the Year
Carolyn Wilke | Dec 21, 2018
From 500-million-year-old fat to a newly discovered virus, here are some stunners from The Scientist in 2018.
Claim of First Gene-Edited Babies Triggers Investigation
Claim of First Gene-Edited Babies Triggers Investigation
Catherine Offord | Nov 26, 2018
He Jiankui says he has successfully used CRISPR-Cas9 to tweak the genes of twins born earlier this month. Some independent experts are dubious.