A corn snake against a black background. Comparative genomics and CRISPR-Cas9 helped identify the genes that give it its characteristic dorsal blotches.

| 4 min read

How Do Snakes Get Their Colorful Stripes and Blotches?

Comparing the genomes of snakes with distinct coloration patterns pinpointed the genetic variants that contribute to these intricate designs.

Illustration depicting DNA genetic engineering, purple background with white drawings of internal organs like liver, lung, kidney, brain, intestine, stomach and a red heart featuring two orange DNA helices being cut by labcoat-covered arms and hands, which are holding different instruments to cut the helices.

| 4 min read

Ancestry Bias Could Cause CRISPR Screens to Veer Off-target

3D illustration of the cross section of an exosome showing a purple double-membrane, blue proteins inside and on the surface of the vesicle, and red nucleic acid. There are two other exosomes to the right, not as cross sections.

| 2 min read

Molecular Barcodes Help Identify Genes Crucial for Extracellular Vesicle Release

CRISPR/Cas

A CRISPR-Cas platform uses microfluidic droplets, encasing CRISPR components and DNA barcodes, and injects individual droplets into zebrafish embryos. The embryos are raised and then researchers link phenotypes to genotypes by sequencing the barcodes.

DNA Droplets in Motion Accelerate Gene Discovery

Laura Tran, PhD | | 1 min read

Graphic showing Cas9 introducing blunt end double-strand breaks in DNA while Cas12a introduces staggered cuts in the DNA.

What’s the Difference Between Cas9 and Cas12a Nucleases?

Danielle Gerhard, PhD | | 2 min read

istock

Reaching New Heights with Genetic Engineering Techniques

Thermo Fisher ScientificandThe Scientist | | 1 min read

Image of Brussels sprouts and endives on a wooden background.

Greens and Genes: The Bitter Truth Behind Your Veggie Preferences

Laura Tran, PhD | | 5 min read

An illustration of a perforated grey nucleus holding colorful spaghetti-like DNA strands.

Gene Proximity to Nuclear Speckles Drives Efficient mRNA Splicing

Karen Kelley Perkins, PhD | | 4 min read

Lonza and Vertex Sign a Long-Term Commercial Supply Agreement for CASGEVY® (exagamglogene autotemcel)

Lonza | | 2 min read

A conceptual illustration of scissors, which represents a CRISPR-Cas9 complex, cutting a DNA molecule.

Cell Engineering 101: Editing with CRISPR

EditCo | | 1 min read

Two cells on a purple background. Two mechanisms of gene silencing are shown in the cell on the left, while a double-strand break in a DNA region is shown in the cell on the right.

What’s the Difference Between Gene Knockdown and Gene Knockout?

Mariella Bodemeier Loayza Careaga, PhD | | 2 min read

Neurons in culture

Lighting Up the Neuronal Cytoskeleton

Mariella Bodemeier Loayza Careaga, PhD | | 2 min read

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Trending

An old medical illustration features the ear in the center with nerves of the head shown in yellow.

The Ear as a Therapeutic Gateway to the Vagus Nerve

Auricular vagal neuromodulation therapy is a non-invasive and non-surgical treatment that could aid cardiovascular disease management, Long COVID relief, and more.

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

3D illustration showing three differently colored semi-translucent cells, representing different T cell subtypes, on a black background. A purple cell is in the front on the right, a red cell is on the left, and a blue cell sits behind the red one.

T Cell Nomenclature Gets an Update

Improved technologies have allowed researchers to delve deeper into T cell biology, but the traditional naming scheme has struggled to keep up with new findings.

A yellow-colored frozen frog.

Freeze-Tolerant Frogs Power Organ Cryopreservation Strategies

Frogs that freeze themselves solid in the winter and thaw in the spring inspired methods to extend the storage time for transplantable organs.

Multimedia

Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

In this webinar, Andre Mueller will discuss how scientists characterize therapeutic proteins in different formulations and spot the effects of excipients on protein stability.

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Scientific X and S Series General Purpose Centrifuges are designed to help provide exceptional performance, versatility and enhanced sustainability.

Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.

January 2026, Issue 1

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

View this Issue

Research Resources

Podcasts

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Skip the Wait for Protein Stability Data with Aunty

Skip the Wait for Protein Stability Data with Aunty

In this webinar, Andre Mueller will discuss how scientists characterize therapeutic proteins in different formulations and spot the effects of excipients on protein stability.

Graphic of three DNA helices in various colors

An Automated DNA-to-Data Framework for Production-Scale Sequencing

A streamlined, automated process helps scientists coordinate site-ready production-level whole genome sequencing results.

Exploring Cellular Organization with Spatial Proteomics

Exploring Cellular Organization with Spatial Proteomics

In this webinar, learn how scientists are using cutting-edge spatial proteomics technologies to advance their understanding of cellular organization in healthy and diseased tissues.

Abstract illustration of spheres with multiple layers, representing endoderm, ectoderm, and mesoderm derived organoids

Organoid Origins and How to Grow Them

Scientists rely on cytokines, growth factors, and other agents to direct and create different types of organoid models.

Products

Product News

BRANDTECH Scientific Introduces the Transferpette® pro Micropipette: A New Twist on Comfort and Control

The Transferpette® pro expands the Transferpette® family, offering scientists even greater flexibility to match their pipetting preferences and workflow requirements.

Biotium Launches GlycoLiner™ Cell Surface Glycoprotein Labeling Kits for Rapid and Selective Cell Surface Imaging

Fast, gentle, and highly specific glycoprotein labeling compatible with downstream immunofluorescence, enabled by next-generation aminooxy chemistry.

Colorful abstract spiral dot pattern on a black background

Thermo Scientific X and S Series General Purpose Centrifuges

Thermo Scientific X and S Series General Purpose Centrifuges are designed to help provide exceptional performance, versatility and enhanced sustainability.

Abstract background with red and blue laser lights

VANTAstar Flexible microplate reader with simplified workflows

VANTAstar Flexible microplate reader with simplified workflows