CRISPR/Cas
Researchers Discover 10 New Immune Systems in Bacteria
Researchers Discover 10 New Immune Systems in Bacteria
Jim Daley | Jan 25, 2018
The findings more than double the number of known defense mechanisms, piquing the interests of molecular biology tool developers.
Immunity May Make CRISPR-Based Therapies Ineffective
Immunity May Make CRISPR-Based Therapies Ineffective
Jim Daley | Jan 10, 2018
Researchers identify antibodies for two commonly used Cas9 proteins in human blood. Investors take notice.
2017 in Quotes
2017 in Quotes
Catherine Offord | Dec 28, 2017
Gender discrimination, Brexit, and climate change are among the issues that have received considerable attention from the scientific community this year.
Top Technical Advances in 2017
Top Technical Advances in 2017
Shawna Williams | Dec 24, 2017
The year’s most impressive achievements include new methods to extend CRISPR editing, patch-clamp neurons hands-free, and analyze the contents of live cells.
CRISPR Proves Promising for Treating ALS in Mice
CRISPR Proves Promising for Treating ALS in Mice
Katarina Zimmer | Dec 21, 2017
The gene-editing tool was effective in disabling a defective gene responsible for some forms of amyotrophic lateral sclerosis. 
CRISPR to Debut in Clinical Trials
CRISPR to Debut in Clinical Trials
Diana Kwon | Dec 14, 2017
The first industry-sponsored CRISPR therapy is slated to be tested in humans in 2018.
2017 Top 10 Innovations
2017 Top 10 Innovations
The Scientist Staff | Dec 1, 2017
From single-cell analysis to whole-genome sequencing, this year's best new products shine on many levels.
RNA Editing Possible with CRISPR-Cas13
RNA Editing Possible with CRISPR-Cas13
Ruth Williams | Oct 25, 2017
Scientists extend the capabilities of the CRISPR-Cas system to include precise manipulations of RNA sequences in human cells.
Base Editing Now Able to Convert Adenine-Thymine to Guanine-Cytosine
Base Editing Now Able to Convert Adenine-Thymine to Guanine-Cytosine
Catherine Offord | Oct 25, 2017
With the arrival of a new class of single-nucleotide editors, researchers can target the most common type of pathogenic SNP in humans.
Image of the Day: CRISPR on a Mouse Canvas
Image of the Day: CRISPR on a Mouse Canvas
The Scientist Staff, The Scientist Staff | Oct 25, 2017
Scientists are using CRISPR-Cas9 technology to tag and explore specific sets of neurons in mice, in one of the first steps towards building a comprehensive atlas of brain circuitry.