Researchers use a new way to deliver CRISPR/Cas9 to tumors in mice, wiping out the cancer.
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Special stealth liposomes with a polyethylene glycol (PEG) coating that serves to hide the liposomes from the immune system are injected into mice with tumors (1). There, the PEG covering spontaneously falls off (2), allowing the liposomes to merge with cells and deliver CRISPR-Cas9 gene editing machinery (3). The system is designed to slice the powerful oncogene E7 (4), triggering apoptosis (5) and wiping out the tumors.
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In mammals, intracellular clocks begin to tick within days of fertilization.
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Slow temperature recovery can threaten the integrity of your work. That’s Stirling Ultracold designed the VAULT100™ to operate at setpoints down to -100°C, so your samples may never be exposed to temperatures above -70°C during a typical door opening.
