Researchers use a new way to deliver CRISPR/Cas9 to tumors in mice, wiping out the cancer.
Special stealth liposomes with a polyethylene glycol (PEG) coating that serves to hide the liposomes from the immune system are injected into mice with tumors (1). There, the PEG covering spontaneously falls off (2), allowing the liposomes to merge with cells and deliver CRISPR-Cas9 gene editing machinery (3). The system is designed to slice the powerful oncogene E7 (4), triggering apoptosis (5) and wiping out the tumors.
Read the full story.
Add The Scientist as a preferred Google source to see more of our trusted coverage.
After earning a bachelor’s degree in biology and neuroscience from Williams College, Rachael spent two years studying the tiny C. elegans worm as a lab tech at Massachusetts General Hospital/Harvard University. She then returned to school to get a master’s degree in environmental studies from Brown University, and subsequently worked as an intern at Scientific American, Discover magazine, and the Annals of Improbable Research, the originators of the yearly Ig Nobel prizes. She now freelances for both scientific and lay publications, and loves telling the stories behind the science. Find her at rachaelgorman.com or on Instagram @
When Barry Hicks set out to photograph thrombolites, thousands of unexpected visitors photobombed his underwater images.
View this Issue
Explore emerging mechanisms of immune checkpoint inhibitor resistance in hepatocellular carcinoma (HCC) and how combination immunotherapy strategies may improve antitumor immune responses and patient-specific treatment approaches.
Learn practical strategies for optimizing sample preparation, fragmentation, library construction, and quality control to generate high-quality next-generation sequencing (NGS) data across a range of sample types.
Learn how bulk T-cell receptor (TCR) repertoire sequencing can reveal clonotype diversity, support immune monitoring, and generate biological insights for translational immunology and biomarker discovery.
Explore how single-cell genotype-to-phenotype mapping can reveal clonal architecture and the functional consequences of somatic mutations in aging human tissues.
Sino Biological’s trial program enables qualified customers to evaluate SuperNuclease Pro in their specific bioprocessing applications, facilitating faster technology assessment and informed decision-making during process development
This release expands on Sino Biological's comprehensive Tau protein product portfolio, designed to accelerate neurodegenerative disease research.
Resipher measures cellular respiration (OCR) continuously in standard 96-well plates inside your incubator, for days to weeks. No media swaps, dyes, or transfers. A live-cell functional readout for drug safety, metabolism, and mitochondrial health.
The Stirling Ultracold VAULT100™ PRO redefines ultra-low temperature storage with reliable -100°C performance, faster recovery, lower operating costs and sustainable operation. Learn how you can protect critical samples without compromise.
