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Week in Review: March 31–April 4

Transcriptional landscape of the fetal brain; how a parasitic worm invades plants; difficulties reproducing “breakthrough” heart regeneration method; oxytocin and dishonesty

Written byTracy Vence
| 3 min read

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ALLEN INSTITUTE FOR BRAIN SCIENCEA team led by investigators at the Allen Institute for Brain Science in Seattle this week (April 2) published in Nature a brain-wide map of gene expression across the developing human brain. The researchers said that their resource could help scientists better understand how human brains develop differently from those of other mammals and to ascertain the roots of disorders like autism.

“There is no doubt that this is a . . . resource that will be of use for many developmental scientists,” said Wieland Huttner, a cell biologist and neurobiologist at the Max Planck Institute of Molecular Cell Biology and Genetics in Dresden, Germany, who was not involved in the work.

WIKIPEDIA, ZYANCEThe parasitic sugarbeet nematode (Heterodera schachtii), which invades the roots of sugar beets, cabbages, and broccoli—causing substantial agricultural damage in some regions—exploits the plants’ defense mechanism in order to successfully infiltrate its host, researchers from the University of Bonn in Germany have found. Their work was published in Science Signaling this week (April 3).

Jeff Dangl from the University of North Carolina at Chapel Hill, who studies plant-pathogen interactions but was not involved in the research, said: “This work gives us new clues as to how we might inhibit the ROS [reactive oxygen species]-producing machinery in the root to inhibit nematode infection, which is ...

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