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Why Women Outlive Men

Mitochondria mutations that affect male, but not female, aging could explain why women tend to live longer than men.

Written byJef Akst
| 1 min read

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Researchers have discovered several mutations in the mitochondrial DNA of Drosophila that affect male lifespan and rate of aging, but have no effect on aging in females, according to a study published this week (August 2) in Current Biology.

According to BBC News, there are about 50 percent more women in the UK population by the age of 85, and twice as many more women by the age of 100. And this pattern is not just limited to humans.

Analyzing the mitochondria of male and female Drosophila melanogaster, Damian Dowling of Monash University in Australia and colleagues found that the mitochondria harbor numerous mutations that affect male, but not female, aging. Because mitochondria are passed down from the mother, evolutionary theory predicts that male-harming mutations can accumulate in its DNA.

“If a mitochondrial mutation occurs that harms fathers, but has no effect on mothers, this mutation will slip through the ...

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Meet the Author

  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

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