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Canada Approves World’s First Plant-Based COVID-19 Vaccine

Canada has ordered 76 million doses of Covifenz, the main ingredient of which was manufactured in the leaves of a tobacco relative.

Written byNatalia Mesa, PhD
| 2 min read
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On Thursday (February 25), Health Canada, the department of the Government of Canada responsible for Canada’s national health policy, approved the world’s first plant-based COVID-19 vaccine for use in adults aged 18 to 64. Too little data exists for approval in adults over 65, the regulators concluded.

Medicago, the Quebec-based pharmaceutical company behind the plant-based jab, has agreed to supply the Canadian government with 76 million doses of the vaccine as soon as possible, the Associated Press reports.

“We're at a stage where we're ramping up capacity to meet the supply agreement,” Marc-André D’Aoust, executive vice president of innovation, development, and medical affairs at Medicago, tells Reuters.

Medicago uses Nicotiana benthamiana, a close relative of the tobacco plant, to manufacture virus-like particles that mimic SARS-CoV-2’s spike protein but don’t cause infection or disease. The particles are then harvested from the plants, purified, and combined with an immune-boosting adjuvant—made by British ...

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Meet the Author

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    As she was completing her graduate thesis on the neuroscience of vision, Natalia found that she loved to talk to other people about how science impacts them. This passion led Natalia to take up writing and science communication, and she has contributed to outlets including Scientific American and the Broad Institute. Natalia completed her PhD in neuroscience at the University of Washington and graduated from Cornell University with a bachelor’s degree in biological sciences. She was previously an intern at The Scientist, and currently freelances from her home in Seattle. 

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