Cardiac Cell Transplants Help Monkeys’ Hearts

The organ’s blood-pumping capacity improved with the infusion of cells, a study shows.

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Injecting human cardiac muscle cells into monkeys that suffered heart attacks helped the animals’ damaged hearts pump blood better, researchers report July 2 in Nature Biotechnology. The treatment is based on the reprogramming of human embryonic stem cells, and the results move the therapy a step closer to clinical trials.

“We're talking about the number one cause of death in the world [for humans],” study author Charles Murry, director of the Institute for Stem Cell and Regenerative Medicine at the University of Washington, tells CNN. “And at the moment all of our treatments are . . . dancing around the root problem, which is that you don't have enough muscle cells.”

When a heart attack goes untreated, blood is blocked from flowing to the heart, which leads to the death of heart muscle cells. There can also be scarring and heart failure—when the heart cannot pump enough blood to the ...

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Meet the Author

  • Ashley Yeager

    Ashley started at The Scientist in 2018. Before joining the staff, she worked as a freelance editor and writer, a writer at the Simons Foundation, and a web producer at Science News, among other positions. She holds a bachelor’s degree in journalism from the University of Tennessee, Knoxville, and a master’s degree in science writing from MIT. Ashley edits the Scientist to Watch and Profile sections of the magazine and writes news, features, and other stories for both online and print.

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