THE INSTITUTE OF CANCER RESEARCH, LONDON
Chris Marshall, whose worked uncovered the oncogene NRAS and characterized the role of the RAS protein in cell division and cancer, died of colorectal cancer on August 8. He was 66.
“His research paved the way for four new classes of cancer drug to enter the clinic, two of which have been approved for widespread use in patient treatment today,” according to an announcement by the Institute of Cancer Research, where Marshall served multiple roles since 1980, including director of research and the head of cancer biology.
Marshall’s early work on NRAS was done in collaboration with the late Alan Hall. In a memorial of Hall, Marshall earlier this year recounted the frustration he and his colleague felt when looking for human genes that could ...