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cell signaling

Surface rendering of microscopy image showing two dendritic cells (green) communicating with a nociceptor neuron (violet).

How Cells in the Skin Team Up To Fight Pathogens

Rachael Moeller Gorman | Apr 12, 2023 | 4 min read

Immune cells and pain neurons form complex partnerships to protect our bodies from pathogens, new research reveals.

Mother’s Circadian Rhythms Mirrored in Fetal Rat Brains

Bianca Nogrady | Sep 12, 2022 | 2 min read

Before their own central clocks develop, the brains of fetal rats detect their mother’s metabolic cycle to help regulate the expression of certain genes.

An immunoglobulin, also known as an antibody, floating in solution.

Shining a Light on Mass Photometry

The Scientist’s Creative Services Team and Refeyn | 3 min read

Mass photometry is an interferometric scattering-based technique offering researchers unprecedented characterization of biomolecular complexes and oligomerization in physiologically-relevant situations.

A micrograph of the prion-like state of a protein called Pus4

Protein Mediates Non-Genetic Inheritance of Growth Strategies

Catherine Offord | Jan 4, 2022 | 2 min read

An RNA-modifying enzyme passed to daughter cells during budding allows yeast cells to switch between faster- and slower-growing phenotypes.

Image of fruit fly epithelial cells (pseudo colored in this micrograph)

Epithelial Cell Signaling Helps Maintain Tissue Integrity

Annie Melchor | Nov 1, 2021 | 2 min read

Using a transgenic fruit fly model, researchers demonstrate how epithelial barriers are maintained in living organisms despite high levels of cell turnover and death.

Discover how glycosylation affects health and disease

Exploring the World of Glycobiology

The Scientist’s Creative Services Team and Vector Laboratories | 1 min read

Researchers study sugar modifications to understand health and disease.

An illustration of a yeast cell (right) and a human neuron (left) showing the processes/features that are similar in the two

Infographic: Modeling Neurodegenerative Diseases with Yeast

Mahlon Collins | Oct 1, 2021 | 3 min read

Conservation of structures and functions between single-celled fungi and human cells allow researchers to probe the brain.

Photograph of a mouse covering his face with his paw.

Bless You: Mouse Model Reveals Molecular Pathway Behind Sneezing

Amanda Heidt | Oct 1, 2021 | 3 min read

Researchers have identified specific cells and neuropeptides involved in mediating the sneeze response in mice exposed to allergens or chemical irritants such as capsaicin.

It’s Bittersweet: The Tumorigenic Potential of Glycosylation

The Scientist Creative Services Team in collaboration with Vector Laboratories | 1 min read

Karen Abbott and Susan Bellis discuss how to detect and block tumorigenic glycosylation signatures to diagnose and treat cancer.

Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.

Yeast Models Provide New Insights into Neurodegenerative Diseases

Mahlon Collins | Oct 1, 2021 | 10+ min read

The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.

Illustration showing how a mouse study identifies the brain regions and specific signaling factors that regulate the sneeze response.

Infographic: The Neural Pathway of Sneezing

Amanda Heidt | Oct 1, 2021 | 1 min read

A mouse study identifies the brain regions and specific signaling factors that regulate the sneeze response.

Discover how to scale up cellular assays during drug discovery

High-Throughput Solutions for Lead Candidate Discovery

The Scientist’s Creative Services Team and Thermo Fisher Scientific | 1 min read

New technologies allow researchers to scale up assays for cellular functions.

A scanning electron micrograph of a coculture of E. coli and Acinetobacter baylyi. Nanotubes can be seen extending from the E. coli.

What’s the Deal with Bacterial Nanotubes?

Sruthi S. Balakrishnan | Jun 1, 2021 | 10+ min read

Several labs have reported the formation of bacterial nanotubes under different, often contrasting conditions. What are these structures and why are they so hard to reproduce?

Drawing of the three kinds of glycosylated cell surface biomolecules: glycoproteins, glycolipids, and now, glycoRNAs

Newly Discovered Glycosylated RNA Is All Over Cells: Study

Christie Wilcox, PhD | May 18, 2021 | 8 min read

Prior to a 2019 preprint, “glycoRNAs” weren’t known to exist. Now, the researchers who found them say they’re on lots of cells and may play a role in immune signaling.

Understanding the Complexity of Cancer with Cryo-EM

The Scientist’s Creative Services Team and Thermo Fisher Scientific | 1 min read

Explore how researchers use cryogenic electron microscopy (cryo-EM) to identify how mutations affect protein signaling and function through structural or conformational changes.

High Stress Hormone Levels Halt Mouse Fur Growth

Jef Akst | Apr 1, 2021 | 4 min read

Corticosterone interferes with signaling in the skin that normally activates hair follicle stem cells, possibly explaining the link between stress and hair loss.

New Understanding of Metastasis Could Lead to Better Treatments

Shawna Williams | Apr 1, 2021 | 10+ min read

Recent insights, such as the recognition that disseminated cancer cells can lie dormant for years before seeding secondary tumors, suggest novel strategies for fighting metastatic disease.