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Overcoming Immunotherapy Resistance in Liver Cancer
Event Date:
Explore emerging mechanisms of immune checkpoint inhibitor resistance in hepatocellular carcinoma (HCC) and how combination immunotherapy strategies may improve antitumor immune responses and patient-specific treatment approaches.
Axion Biosystems

cell signaling

A picture of Shambhu Yadav, a postdoc at Brigham and Women’s Hospital and Harvard Medical School.

Postdoc Portrait: Shambhu Yadav

Targeting RGS14 with AI-Guided Docking and Biochemical Assays

Targeting RGS14 with AI-Guided Docking and Biochemical Assays

Bellbrook Labs 
Antibodies block the interaction between PD-L1 (on the surface of a cancer cell) and PD-1 (on the surface of a T cell).

Studying Immune Checkpoint Signaling to Fight Cancer

Sino
Capturing 3D Cell Biology in Its Natural Environment

Capturing 3D Cell Biology in Its Natural Environment

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A 3D rendered image of an antibody modeled after its Y-shaped protein structure.

Functional Antibodies Drive Disease Research

The lipid bilayer with embedded transmembrane channel proteins and glycoproteins.

Unlocking the Drug Discovery Potential of Membrane Proteins

A 3D illustration of vaccine for cancer as oncology treatment concept.

A Novel Engineered Protein Boosts T Cell Antitumor Activity

The three-dimensional structure of a GPCR protein, with pink and blue shaded alpha helices

G Protein-Coupled Receptors and Their Role as Drug Targets

Epithelial cells (green) produce electrical signals in response to laser-induced wounds (bright spots).

Skin Cells Create Neuron-Like Electric Signals

Trending

A team of cartoon scientists studying a giant pancreas.

Prolonged GLP-1 Exposure Remodels Gene Expression in the Pancreas by Flipping a Molecular Switch

A drawing of men and women holding boxes, resigning en mass from their jobs as editors.

Editors Mass Resign from Elsevier Journal After Editor-in-Chief Let Go

Image of a Diploptera punctata cockroach.

Cockroach Milk Proteins Churn Out an Ig Nobel Win

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

Multimedia

Essential Genes Are Dominantly Activated by Single Transcription Factors

Essential Genes Are Dominantly Activated by Single Transcription Factors

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Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

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The Scientist Digest cover September 2026
September 2026

Multiplex Microscopy Becomes Easier with Encoded Antibodies

A new system that enables researchers to uniquely tag monoclonal antibodies for use in microscopy could help simplify complex imaging studies.

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Essential Genes Are Dominantly Activated by Single Transcription Factors

Essential Genes Are Dominantly Activated by Single Transcription Factors

EpiCypher Logo
Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Rethinking ALS Biomarkers: From Discovery to Clinical Impact

Alamar Biosciences logo
Engineering CAR-Neutrophils In Vivo to Target Glioblastoma

Engineering CAR-Neutrophils In Vivo to Target Glioblastoma

Miltenyi
Best Practices for qPCR Assay Design and Optimization

Best Practices for qPCR Assay Design and Optimization

Bio-Rad

Products

Closeup image of a multi channel pipette dispensing pink liquid into a 96-well plate.

The ASSIST PLUS pipetting robot for affordable workflow automation

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Single cells in suspension

Rapidly isolate primary cells and make uniform single-cell suspensions with Corning® Cell Strainers

Corning logo
Abstract image representing cell membranes linked together.

CellBrite® Steady Membrane Stain: Cell surface staining built for real-time imaging

Biotium
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Monod Bio Licenses AI-designed Protein Technologies to SignalChem Biotech for Custom Discovery Assays