Antibodies block the interaction between PD-L1 (on the surface of a cancer cell) and PD-1 (on the surface of a T cell).

| 3 min read

Studying Immune Checkpoint Signaling to Fight Cancer

A better understanding of immune checkpoint signaling can help improve future checkpoint inhibitor therapeutic approaches.

Capturing 3D Cell Biology in Its Natural Environment

Available on Demand

Capturing 3D Cell Biology in Its Natural Environment

A 3D rendered image of an antibody modeled after its Y-shaped protein structure.

| 3 min read

Functional Antibodies Drive Disease Research

cell signaling

The lipid bilayer with embedded transmembrane channel proteins and glycoproteins.

Unlocking the Drug Discovery Potential of Membrane Proteins

The Scientist StaffandNuclera | | 4 min read

A 3D illustration of vaccine for cancer as oncology treatment concept.

A Novel Engineered Protein Boosts T Cell Antitumor Activity

Sneha Khedkar | | 3 min read

The three-dimensional structure of a GPCR protein, with pink and blue shaded alpha helices

G Protein-Coupled Receptors and Their Role as Drug Targets

Rebecca Roberts, PhD | | 6 min read

Epithelial cells (green) produce electrical signals in response to laser-induced wounds (bright spots).

Skin Cells Create Neuron-Like Electric Signals

Sahana Sitaraman, PhD | | 3 min read

A person sitting in a gym with a protein shake bottle and kettlebell placed beside them.

Exerkines: Molecular Messengers That Mediate Exercise Effects

Sneha Khedkar | | 6 min read

A conceptual illustration of scientists evaluating potential kinase inhibitors.

Leveraging Recombinant Kinases for Drug Discovery Research

The ScientistandSino Biological | | 3 min read

A 3D artist’s rendition of a macrophage.

What Drives Myeloid Cell Responses to Disease

Bio X CellandThe Scientist | | 3 min read

Explore How High-plex Protein Profiling Contributes to Disease Research

Using High-plex Protein Profiling to Discover Links Between Genes and Disease

SomaLogic | | 1 min read

Discover How Protein Sequencing Evolves to Accelerate Research

The Future of Protein Sequencing

Quantum Si | | 1 min read

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Trending

A cross section of a pine stem shows cells stained purple and blue.

The Biggest Breakthroughs in Cell Biology in 2025

From microglia reprogramming to immune cell-based diagnostics, 2025 was a big year for breakthroughs in cell biology.

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

Gollum, the extremely territorial character from The Lord of the Rings, famous for his line, “My precious,” sits on a rock, looking up.

The Gollum Effect: 44 Percent of Scientists Report Territorial Research Experiences

Survey data showed that hoarding research topics and resources, termed the Gollum effect, has a lasting impact on trainees and perpetuates a toxic research culture.

person doing the finger prick test for measuring blood glucose. A new noninvasive method could provide an alternative to such invasive blood tests.

Measuring Blood Sugar Without Painful Pricks? A New Test Scans Skin

Shining near-infrared light on a person’s skin helped scientists accurately track his blood glucose levels, offering a potential noninvasive way to monitor diabetes.

Multimedia

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

December digest cover image of a wooden sculpture comprised of multiple wooden neurons that form a seahorse.

December 2025, Issue 1

Wooden Neurons: An Artistic Vision of the Brain

A neurobiologist, who loves the morphology of cells, turns these shapes into works of art made from wood.

View this Issue

Research Resources

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eBooks

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Explore the latest in cell culture supplies, from tried and tested classics to cutting-edge innovative products.

Human iPSC-derived Models for Brain Disease Research

Human iPSC-derived Models for Neurodegenerative Disease Research

In this webinar, Jesús Tintos-Hernandez, Setsu Endoh-Yamagami, and Amaris Castañon will discuss the latest advances and innovations in neuroscience disease cell models.

Abstract wireframe sphere with colorful dots and connecting lines representing the complex cellular and molecular interactions within the tumor microenvironment.

Exploring the Inflammatory Tumor Microenvironment

Within the tumor microenvironment, networks of cells and molecular signals form a dynamic landscape that drives disease progression.

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BRANDTECH® Scientific Announces Strategic Partnership with Copia Scientific to Strengthen Sales and Service of the BRAND® Liquid Handling Station (LHS)

This partnership will enable both companies to reach a broader range of customers, including those with more complex and specialized workflows

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Enter Our 2026 Top Innovations Contest

Submit a cutting-edge product or technology for the chance to be recognized as one of The Scientist’s 2026 Top Innovations.

Biotium Expands Tyramide Signal Amplification Portfolio with Brighter and More Stable Dyes for Enhanced Spatial Imaging

Biotium's new TyraMax™ Amplification Dyes and Kits are available with the widest selection of colors for spatial analysis

LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS

Ten-year Agreement to Provide a Secure, AI-enabled Forensic Laboratory Information Management System Supporting DHS Forensic, Scientific, and Testing Services