March cover for The Scientist

March 2025

Peto's Paradox: How Gigantic Species Evolved to Beat Cancer

Scientists dive into the genomes of whales, elephants, and other animal giants looking for new weapons in the fight against cancer.

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Features

Illustration of a young adult looking at their phone as they walk through an arrow that is pointing up. An illustration of a colon is in the background.

Generation X and Millennials Face a Steep Rise in Early-Onset Colorectal Cancer Cases

Illustration of transplanted beta-cell islets and surveilling host immune cells.

Cell Therapy is Poised for Sweet Victory in Diabetes

A red male cardinal and a brownish female sit on a branch in front of a green background.

Sex Determination: It’s in the Genes—Sometimes

A group of large animals, some of which are being studied for cancer resistance genes and proteins, are pictured, including a bison, an elephant, a giraffe, a manatee, a zebra, and a whale.

Peto’s Paradox: How Gigantic Species Evolved to Beat Cancer

Image of a forensic scientist holding a magnifying glass to DNA to reveal a DNA fingerprint.

DNA Profiling: Tracing Killers and Solving Mysteries Using Genetic Clues

Infographics

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Advancing Stem Cell Therapy for Diabetes Treatment

Illustration depicting a series of environmental exposure, such as a poor diet and pollution, that can occur throughout an individual's lifetime and have lasting impacts on cells and molecules.

A Lifetime of Environmental Exposures May Be Fueling Early-Onset Cancers

Illustration of a manatee, capybara, whale and elephant

Anticancer Inspiration from Animal Giants

Speaking of Science

March 2025 Crossword

Cancer Culture

Editorial

Yin and yang symbols made of stones and lines in the sand.

The Yin and Yang of Cancer 

Contributors

Image of Hannah Thomasy sitting with her white dog in her lap.

Meet the Team: Hannah Thomasy

Profiles

3D illustration of a yellow tumor in the bottom left corner on a black background. A gold liposome toward the top right of the image delivers pink, multi-faceted diamonds representing a nanodrug to attack the tumor.

Tuning Cancer Therapy with Acoustic Drug Delivery

Foundations

Illustration of two TALENs bound to DNA. Repetitive helices wrap around DNA and bind at dedicated sites in each repeat. An enzymatic nuclease domain attached to each TALEN allows for cutting of one strand of the DNA.

A Tale of How TALENs Launched the Genome Editing Revolution

Cartoon showing three scientists pulling a rope that is attached to the hand of a clock, symbolizing their efforts to turn back time.

Pluripotency Superstar Oct4 Gets a Makeover

Illustration of a developing fetus surrounded by a clear fluid with a subtle yellow tinge, representing amniotic fluid.
January 2026

What Is the Amniotic Fluid Composed of?

The liquid world of fetal development provides a rich source of nutrition and protection tailored to meet the needs of the growing fetus.

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Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

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Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

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Products

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Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

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Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

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Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies

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Parse Biosciences and Graph Therapeutics Partner to Build Large Functional Immune Perturbation Atlas