Reeling in Painkillers

Me, Myself, and Why, RedDevil 4, Neanderthal Man, and Science from Sight to Insight

Graduate programs at the interface of quantitative and biological sciences set the stage for more interdisciplinary collaboration.
 

Electron microscopy led to the first identification of what would later be known as ribosomes.

Can practitioners of the Eastern religion learn from biologists, or vice versa?

A guide to DNA-encoded libraries for drug discovery

A tour of techniques for measuring DNA hydroxymethylation

Professor, Chemistry, The Scripps Research Institute. Age: 36

Fueled by her love of visual data and addicted to chromosomes, Abby Dernburg continues to study how homologous chromosomes find each other during gamete formation.

Human papillomavirus promotes genomic damage by inserting near host genes involved in cancer.

A mouse knockout calls into question the presumed function of a protein long considered important for steroid hormone biosynthesis.

Repairing damaged neurons relies on booting a histone deacetylase out of the nucleus so regeneration genes can be turned on.

Scientists devise a gentler technique for observing viral DNA at single-molecule resolution.

Attracting females to research careers—and keeping them there

Until health care becomes truly personalized, race and ethnicity will continue to be important clues guiding medical treatments.

Next-generation sequencing of the bacterial assemblages that inhabit a corpse throughout decomposition improve time-of-death estimates.

Formosan subterranean termites evade deadly pathogens by building nests lined with their own feces.

A 50,000-generation-long experiment shows that bacteria keep getting fitter.

Many people can “see” their hands in complete darkness, absent any visual stimulus, due to kinesthetic feedback from their own movements.

February 2014's selection of notable quotes

Developing nonaddictive drugs to combat pain

Meet some of the people featured in the February 2014 issue of The Scientist.

Is it possible to make a nonaddictive opioid painkiller?