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One day, doctors may be able to use the metabolites in blood samples to predict the likelihood of a person surviving another five to 10 years, according to a newly developed tool described today (August 20) in Nature Communications. The authors of the report say the information may be useful in helping decide whether or not to do surgery on patients who are frail or could serve as endpoints in new clinical trials.
The study “shows the potential usefulness of metabolomic biomarkers,” says Paola Sebastiani, a biostatistician at Boston University who was not involved in the study. She adds that the field will need longitudinal studies in the future to assess the biomarkers’ clinical usefulness.
The team’s goal was to find blood-based biomarkers that can “indicate risk of vulnerability, especially if that information provides opportunities for an improvement in lifestyle or better treatment,” says Eline Slagboom, ...