Opinion: Younger Is Better

Stem cells collected from younger donors are more effective for transplantation and regenerative medicine than those from older individuals.

Written byDavid T. Harris
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

Talk of stem cells as medical therapies have become almost commonplace these days. Millions have now collected and stored their stem cells in biobanks for potential future use, and tens of thousands of patients have received stem cell transplants or infusions for the treatment of cancer or various experimental regenerative medicine therapies. It is estimated that the likelihood of a member of your family needing a stem cell transplant for cancer by age 70, using their own cells or someone else’s, is 1 in 217. And the odds of use in regenerative medicine may be even greater.

But often overlooked are the common factors that may impair the utility of these stem cells. Two such factors are stem cell age and donor health. Most therapeutic stem cells are derived from relatives or unrelated donors, and it is often difficult to find suitably matched donors. As a result, the selection criteria ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies