Pneumonia-Causing Bacteria Poke Holes in Heart

Microlesions in heart muscle may contribute to cardiac complications in elderly patients, a study shows.

Written byMolly Sharlach
| 4 min read

Register for free to listen to this article
Listen with Speechify
0:00
4:00
Share

Microlesions near a blood vessel (left) in mouse myocardium are filled with Streptococcus pneumoniae. UTHSCSA, ARMAND BROWN

Older adults who are hospitalized for pneumonia are at high risk for heart problems. About 20 percent of patients experience complications such as congestive heart failure or cardiac arrhythmia, which have been implicated in more than a quarter of pneumonia-related deaths. Along with the low oxygen levels caused by a lung infection, stress on heart muscles may be a direct result of invading bacteria, according to a study published today (September 18) in PLOS Pathogens. Researchers from the University of Texas Health Science Center at San Antonio (UTHSCSA) and their colleagues found that mice and rhesus macaques infected with Streptococcus pneumoniae developed myocardial microlesions, which were also present in human autopsy samples.

“It’s amazing that no one has ever done this before . . . ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

Share
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies