Researchers Succeed in Keeping Disembodied Pig Brains Alive

The organs showed neural activity for up to 36 hours, adding fuel to discussions about the ethics of future neuroscientific research.

Written byCatherine Offord
| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

FLICKR, NICK SALTMARSHA team of US researchers has kept disembodied pig brains alive in a comatose-like state for up to 36 hours, according to a report published last week (April 25) by MIT Technology Review. First revealed by Yale University neuroscientist Nenad Sestan at a meeting held on March 28 at the National Institutes of Health, the results have increased the urgency of the ethical debate surrounding the future of brain research.

Although other groups have managed to keep disembodied brainstems and hearts of rodents alive, the current project is noteworthy for the scale of the brain being preserved, and its apparent success. The results have yet to be published in a scientific journal.

The researchers achieved the feat by experimenting with more than 100 pig brains obtained from a slaughterhouse, Sestan disclosed at the meeting (via MIT Technology Review). While maintaining circulation to the organs with a setup of pumps and heated-up blood, the team observed normal-like patterns of cell activity, even though the brains were only attached to the setup several hours after the pigs were killed—meaning at least some cell death and damage to the organs would be likely.

“These brains may be damaged, ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here

Related Topics

Meet the Author

  • After undergraduate research with spiders at the University of Oxford and graduate research with ants at Princeton University, Catherine left arthropods and academia to become a science journalist. She has worked in various guises at The Scientist since 2016. As Senior Editor, she wrote articles for the online and print publications, and edited the magazine’s Notebook, Careers, and Bio Business sections. She reports on subjects ranging from cellular and molecular biology to research misconduct and science policy. Find more of her work at her website.

    View Full Profile
Share
December digest cover image of a wooden sculpture comprised of multiple wooden neurons that form a seahorse.
December 2025, Issue 1

Wooden Neurons: An Artistic Vision of the Brain

A neurobiologist, who loves the morphology of cells, turns these shapes into works of art made from wood.

View this Issue
Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

Merck
Stacks of cell culture dishes, plates, and flasks with pink cell culture medium on a white background.

Driving Innovation with Cell Culture Essentials

MilliporeSigma purple logo
Abstract wireframe sphere with colorful dots and connecting lines representing the complex cellular and molecular interactions within the tumor microenvironment.

Exploring the Inflammatory Tumor Microenvironment 

Cellecta logo
An image of a DNA sequencing spectrum with a radial blur filter applied.

A Comprehensive Guide to Next-Generation Sequencing

Integra Logo

Products

brandtech logo

BRANDTECH® Scientific Announces Strategic Partnership with Copia Scientific to Strengthen Sales and Service of the BRAND® Liquid Handling Station (LHS) 

Top Innovations 2026 Contest Image

Enter Our 2026 Top Innovations Contest

Biotium Logo

Biotium Expands Tyramide Signal Amplification Portfolio with Brighter and More Stable Dyes for Enhanced Spatial Imaging

Labvantage Logo

LabVantage Solutions Awarded $22.3 Million U.S Customs and Border Protection Contract to Deliver Next-Generation Forensic LIMS