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Conceptual illustration of personalized medicine with medical icons next to a human face.
The Largest Whole-genome Sequencing Study in Cancer 
Comprehensive genome sequencing of 13,880 tumors revealed somatic and germline mutations that could influence patient treatment and prognosis.
The Largest Whole-genome Sequencing Study in Cancer 
The Largest Whole-genome Sequencing Study in Cancer 

Comprehensive genome sequencing of 13,880 tumors revealed somatic and germline mutations that could influence patient treatment and prognosis.

Comprehensive genome sequencing of 13,880 tumors revealed somatic and germline mutations that could influence patient treatment and prognosis.

bioinformatics

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Unearthing Hidden Family Secrets: Tracing the Lineage of a Centuries-Old Grand-Mummy
Iris Kulbatski, PhD | Dec 13, 2022 | 3 min read
Researchers show how a toxic therapy helped identify a mummy using preserved DNA.
multicolor DNA sequencing gel
Genetic Mutations Can Be Benign or Cancerous—a New Method to Differentiate Between Them Could Lead to Better Treatments
Ryan Layer, The Conversation | May 27, 2022 | 5 min read
Tumors contain thousands of genetic changes, but only a few are actually cancer-causing. A quicker way to identify these driver mutations could lead to more targeted cancer treatments.
Comprehensive Quality Control and Interactive Analysis of Single Cell RNA-seq Data
Comprehensive Quality Control and Interactive Analysis of Single Cell RNA-seq Data
The Scientist | 1 min read
In this webinar, Joshua Campbell will talk about the fundamentals of scRNA-seq analysis and how to handle various challenges. 
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Laurence “Larry” Kedes, Molecular Geneticist, Dies at 83
Amanda Heidt | Apr 26, 2021 | 4 min read
In addition to isolating the first protein-coding gene from a eukaryote, Kedes furthered scientists’ understanding of actin genes and also laid the foundations for modern DNA databases such as GenBank.
obituary, obituaries, roundup, end of the year, COVID-19, SARS-CoV-2, pandemic, coronavirus, immunology, genetics & genomics, cell & molecular biology, HIV
Those We Lost in 2020
Amanda Heidt | Dec 18, 2020 | 7 min read
The scientific community bid farewell to researchers who furthered the fields of molecular biology, virology, sleep science, and immunology, among others.
Team of Medical Research Scientists Collectively Working on a New Generation Experimental Drug Treatment. Laboratory Looks Busy, Bright and Modern.
Next-Generation Sequencing: A World without Limits
The Scientist and Illumina | 5 min read
Centralized core facilities and commercial service providers specializing in NGS provide expertise and training for researchers new to the method.
Q&A, functional genomics, genetic privacy, bioinformatics, data science, Yale School of Medicine, Genetics & Genomics
Q&A: A New Tool for Ensuring Genetic Privacy
Amanda Heidt | Nov 12, 2020 | 6 min read
Gamze Gursoy and Mark Gerstein of Yale Medical School have developed a strategy for stripping identifying variants from functional genomic data, balancing privacy with utility.
Computational Biologist James Taylor Dies
Lisa Winter | Apr 7, 2020 | 2 min read
The Johns Hopkins University professor was a co-developer of the Galaxy platform, an open-source bioinformatics tool used in labs around the world.
Profiling Microbes in Their Environmental Context
Profiling Microbes in Their Environmental Context
The Scientist | 1 min read
In this webinar, an expert panel will discuss nucleic acid recovery and sequencing methods from biological samples found in unusual habitats.
Otto Cordero
Otto Cordero Studies Bacteria in the Wild
Catherine Offord | Jun 1, 2019 | 3 min read
The MIT associate professor wants to understand microbial communities in their ecological context.
Opinion: We Must Make Data More Accessible for Bioinformatics Training
David W. Craig | Apr 1, 2018 | 5 min read
In addition to programs geared towards transforming biologists into bioinformaticians, students need more raw material available for their education.
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Revealing Neuronal Influencers Among the Gut Microbiome
The Scientist | 1 min read
In this webinar, Sarkis Mazmanian and Daniel Mucida highlight how intestinal bacteria influence neuronal function and regeneration.
Pocket-Size Nanopore Device Sequences Entire Human Genome
Jim Daley | Jan 29, 2018 | 1 min read
MinION achieved the longest reads of DNA sequences to date. 
Scientists Continue to Use Outdated Methods
Catherine Offord | Jan 8, 2018 | 7 min read
The use of underperforming computational tools is a major offender in science’s reproducibility crisis—and there’s growing momentum to avoid it.
Sorting the Clusters: Creating an Optimized Gating Strategy for Cell Sorting
Sorting the Clusters: Creating an Optimized Gating Strategy for Cell Sorting
The Scientist and BD Biosciences | 1 min read
Rafael Gomez-Amaro and Karen Ersland discuss how HyperFinder technology optimizes cell identification and isolation from flow cytometry assays.
Discovering Novel Antibiotics
Sandeep Ravindran | Feb 1, 2017 | 7 min read
Three methods identify and activate silent bacterial gene clusters to uncover new drugs
How to Build Bioinformatic Pipelines Using Galaxy
Jeffrey M. Perkel | Aug 1, 2016 | 7 min read
A point-and-click interface alternative to command-line tools that allows researchers to easily create, run, and troubleshoot serial sequence analyses
Discover Genetic Influences on the Immune Response
The Genetics Behind Immune Response Variability
The Scientist | 1 min read
Researchers seek genomic clues to understand differences in the immune response to infection.
Learning Bioinformatics
Esther Landhuis | Jul 1, 2016 | 8 min read
In today’s data-heavy research environment, wet-lab scientists can benefit from new computational skills.
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