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A colored microscopy image showing cells that are dying in yellow and healthy cells in blue
Sweet Taste Receptors Regulate Proteins in Developing Fruit Flies
An unexpected find shows that sweet-sensing receptors also help epithelial cells in Drosophila larvae stay alive amid proteotoxic stress.
Sweet Taste Receptors Regulate Proteins in Developing Fruit Flies
Sweet Taste Receptors Regulate Proteins in Developing Fruit Flies

An unexpected find shows that sweet-sensing receptors also help epithelial cells in Drosophila larvae stay alive amid proteotoxic stress.

An unexpected find shows that sweet-sensing receptors also help epithelial cells in Drosophila larvae stay alive amid proteotoxic stress.

epithelial cells
in love with the shape of you
In Love with the Shape of You: Physical Scaffolding Defines Organoid Patterning
Sejal Davla, PhD | Aug 8, 2022 | 3 min read
Controlling a growing tissue’s shape achieves deterministic and uniform patterning in intestinal organoids.
A drawing of pseudostratified gut epithelial cells in the early intestines, cells in red and nucleus in purple.
Move Over Apoptosis: Another Form of Cell Death May Occur in the Gut
Natalia Mesa, PhD | May 18, 2022 | 6 min read
Though scientists don’t yet know much about it, a newly described process called erebosis might have profound implications for how the gut maintains itself.
health care provider standing in front of gynecology stirrups holding swabs for Pap smear
DNA Methylation Could Predict Ovarian, Breast Cancers
Anna Napolitano | Feb 11, 2022 | 5 min read
A pair of new studies finds that analyzing material from a Pap smear can reveal tumor risk in distant parts of the body, potentially allowing early interventions.
Image of fruit fly epithelial cells (pseudo colored in this micrograph)
Epithelial Cell Signaling Helps Maintain Tissue Integrity
Annie Melchor | Nov 1, 2021 | 2 min read
Using a transgenic fruit fly model, researchers demonstrate how epithelial barriers are maintained in living organisms despite high levels of cell turnover and death.
A computer-generated graphic showing a cross-section of red-colored bacteria, with the locations of the protein APOL3 labeled in green.
Human Protein Dissolves Bacterial Membranes
Abby Olena, PhD | Jul 15, 2021 | 4 min read
The protein, apolipoprotein L3, destroys invading microbes by acting as a detergent in the cytosol.
gamma delta t cell intestine gut mouse mice diet nutrient epithelial cell remodeling immune system
Mysterious Immune Cells Change the Gut Lining to Accommodate Diet
Annie Melchor | Apr 6, 2021 | 4 min read
A study shows gamma-delta T cells in mice respond to shifts in nutrients by changing the cellular composition of the intestinal epithelium.
Questions Raised About Widely Used Blood-Brain Barrier Model
Catherine Offord | Feb 16, 2021 | 6 min read
A study has sparked controversy by suggesting that cells made using a popular lab protocol have been misidentified, with potentially serious repercussions for brain research. Critics say the significance of the findings has been overstated.
The Many Model Systems of COVID-19
Abby Olena, PhD | Nov 4, 2020 | 7 min read
Researchers turn to familiar model animals, along with some fresh strategies, to develop countermeasures against SARS-CoV-2 and investigate the biology of infection.
Could Statins Reduce the Severity of COVID-19?
Ashley Yeager | Jun 12, 2020 | 7 min read
The cholesterol-lowering drugs quell inflammation and reverse endothelial tissue damage, hints that they might curb the body’s excessive immune response to SARS-CoV-2 infection.
Chemosensory Cells in the Nose Play a Role in Allergic Reactions
Abby Olena, PhD | Jan 17, 2020 | 3 min read
In mice, a group of nasal epithelial cells called brush cells release pro-inflammatory signals in response to allergens.
Image of the Day: Van Gogh Microscopy
The Scientist Staff and The Scientist Staff | Jan 10, 2018 | 1 min read
Scientists identify the cells that give rise to the soft tissue cancer rhabdomyosarcoma. 
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