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Key Regulator of Intestinal Homeostasis Identified
Diana Kwon | Mar 3, 2017
SP140, an epigenetic reader protein mutated in a number of autoimmune disorders, is essential for macrophage function and preventing intestinal inflammation, scientists show.
Human Gut Microbe Transplant Alters Mouse Behavior
Anna Azvolinsky | Mar 1, 2017
Fecal transplants from humans with irritable bowel syndrome and anxiety into mice lead to similar symptoms and anxiety-like behavior in the rodents, researchers report.
Neonatal Gut Bacteria Might Promote Asthma
Anna Azvolinsky | Sep 12, 2016
Byproducts of gut microbes in some 1-month–old babies trigger inflammation that is linked to later asthma development, researchers find.
One Antigen Receptor Induces Two T cell Types
Ruth Williams | Aug 26, 2016
Precursor T cells bearing the same antigen receptor adopt two different fates in mice.
Antibiotic Therapy During Infancy Increases Type 1 Diabetes Risk in Mice
Alison F. Takemura | Aug 22, 2016
Three therapeutic doses administered during early life disturb the animals’ microbiomes and lead to enduring changes in the immune systems of non-obese diabetic mice, researchers report.
Fecal Transplant Pill Fails Trial
Jef Akst | Aug 1, 2016
Seres Therapeutics’s microbiome-targeting therapy for recurrent
infection fails a Phase 2 clinical trial.
Primates, Gut Microbes Evolved Together
Anna Azvolinsky | Jul 21, 2016
Symbiotic gut bacteria evolved and diverged along with ape and human lineages, researchers find.
Stroke Alters Gut Microbiome, Impacting Recovery
Tanya Lewis | Jul 15, 2016
A bidirectional link between the brain and the gut can improve or worsen brain injury in mice, researchers report.
Tracy Vence | Jun 16, 2016
Analyzing the gut microbiomes of children from birth through toddlerhood, researchers tie compositional changes to birth mode, infant diet, and antibiotic therapy.
Gut Microbiota–Obesity Link Clarified
Catherine Offord | Jun 10, 2016
Changes in diet can cause gut microbes to produce acetate, which in turn stimulates insulin secretion and obesity in rodents, scientists show.