Evidence is mounting that epigenetic marks on DNA can influence future generations in a variety of ways. But how such phenomena might affect large-scale evolutionary processes is hotly debated.

Epigenetic events, such as methylation, during early brain development in mice occur in genomic regions associated with BMI in humans, according to a new study.

Some studies suggest that associations between the health of children and the experiences of their parents or grandparents may be due to epigenetic mechanisms, but confounding factors challenge this interpretation.

The concept of epigenetic inheritance has long been controversial. Some researchers hope that new data on cross-generational effects of environmental exposures will help settle the debate.

A pair of new studies finds that analyzing material from a Pap smear can reveal tumor risk in distant parts of the body, potentially allowing early interventions.

In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.

Cells found in different branches of a tree have different patterns of DNA methylation, changes in which accumulate over time.

Female mice modeling the hormonal disorder can pass symptoms down for several generations, likely via changes in genome methylation that are similarly observed in women with PCOS.

Mouse fathers whose sperm lacks the gene Kdm6a pass down altered methylation patterns to male offspring, along with a better chance of developing tumors and dying.

A clock constructed of rDNA methylation sites can estimate both chronological and biological age across species.

Newly developed techniques could propel a field already advancing rapidly to complement modern medicine.

Emerging technologies help researchers draw mechanistic links between metabolism and epigenetic modification of DNA.

New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.