methylation

The concept of epigenetic inheritance has long been controversial. Some researchers hope that new data on cross-generational effects of environmental exposures will help settle the debate.

A pair of new studies finds that analyzing material from a Pap smear can reveal tumor risk in distant parts of the body, potentially allowing early interventions.

In mice, epigenetic marks made on histones during infancy influence depression-like behavior during adulthood. A drug that reverses the genomic tags appears to undo the damage.

Cells found in different branches of a tree have different patterns of DNA methylation, changes in which accumulate over time.

Female mice modeling the hormonal disorder can pass symptoms down for several generations, likely via changes in genome methylation that are similarly observed in women with PCOS.

Mouse fathers whose sperm lacks the gene Kdm6a pass down altered methylation patterns to male offspring, along with a better chance of developing tumors and dying.

A clock constructed of rDNA methylation sites can estimate both chronological and biological age across species.

Newly developed techniques could propel a field already advancing rapidly to complement modern medicine.

Emerging technologies help researchers draw mechanistic links between metabolism and epigenetic modification of DNA.

New technologies reveal the dynamic changes in mouse and human embryos during the first week after fertilization.

The switch from maternal factors involves dynamic reprogramming of the zygotic genome.

Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.

To expand the basic nucleotide alphabet, many species modify their DNA with epigenetic marks.