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a round water flea is illustrated in black and white on a striated background
Environmental RNA Reveals Heat Stress in Water Fleas
The eRNA detection method could one day be used to catch early warning signs of distress in wild ecosystems. 
Environmental RNA Reveals Heat Stress in Water Fleas
Environmental RNA Reveals Heat Stress in Water Fleas

The eRNA detection method could one day be used to catch early warning signs of distress in wild ecosystems. 

The eRNA detection method could one day be used to catch early warning signs of distress in wild ecosystems. 

molecular biology
Two agar plates superimposed on each other. One is empty while the other is growing multiple different cultured organisms, colored white, beige, and green.
Most Archaea and Bacteria Are Nameless. SeqCode Could Change That
Dan Robitzski | Sep 27, 2022 | 8 min read
The Scientist spoke with microbiologist William Whitman about a new system of nomenclature for prokaryotic organisms that can’t be cultured.
3D rendering of a scanning electron micrograph of pink malignant cancer cells against a black background
Cancers Ramp Up Overall mRNA Expression as They Progress
Dan Robitzski | Jun 14, 2022 | 4 min read
A technique for quantifying tumor mRNA production from messy tissue sample data uncovers an unexpected correlation between it and disease stage in 15 cancer types.
The Fundamentals of Spectral Flow Cytometry
The Fundamentals of Spectral Flow Cytometry
The Scientist’s Creative Services Team | 1 min read
In this webinar, Mirko Corselli discusses the similarities, differences, and advantages of spectral flow cytometry compared to conventional flow.
An illustration showing a scale weighing two double-stranded pieces of DNA that has a big question mark in the center.
Mouse Foraging Behavior Shaped by Opposite-Sex Parent’s Genes
Dan Robitzski | Apr 12, 2022 | 7 min read
A study in mice finds that for certain genes, one parent’s allele can dominate expression and shape behavior—and which parent’s allele does so varies throughout the body.
Deborah Nickerson
Genome Pioneer Deborah Nickerson Dies at 67
Amanda Heidt | Feb 9, 2022 | 3 min read
The University of Washington researcher leveraged data from the Human Genome Project to identify genes underlying various health conditions and advance precision medicine.
The fight against time
The Scientist Speaks - The Fight Against Time: Stem Cells and Healthy Aging 
The Scientist’s Creative Services Team | 2 min read
Tricking the body into mimicking a fasting state may hold the key to fighting age-related cognitive decline. 
Donald Caspar smiling into camera holding a buckyball model
Legendary Crystallographer Donald Caspar Dies At 94
Lisa Winter | Jan 7, 2022 | 2 min read
He coined the term “structural biology.”
A notecard with outdated names of prokaryotic phyla crossed out and replaced with the newer names.
Newly Renamed Prokaryote Phyla Cause Uproar
Dan Robitzski | Jan 4, 2022 | 10+ min read
The International Committee on Systematics of Prokaryotes recently pulled the rank of phylum into its code of official nomenclature. Experts say the move will help standardize science in the long run but potentially disrupt research now.
3D representation of a DNA helix and with a base offset from the main helix, illustrating the concept of base editing.
A CRISPR Alternative for Correcting Mutations That Sensitize Cells to DNA Damage
Deanna MacNeil, PhD | 3 min read
Researchers turned to base editors to correct mutations causing the rare genetic disease Fanconi anemia without inducing double-strand DNA breaks.
An illustration of a yeast cell (right) and a human neuron (left) showing the processes/features that are similar in the two
Infographic: Modeling Neurodegenerative Diseases with Yeast
Mahlon Collins | Oct 1, 2021 | 3 min read
Conservation of structures and functions between single-celled fungi and human cells allow researchers to probe the brain.
Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021 | 10+ min read
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.
stock photo
Cooking up the Perfect PCR Reaction
MilliporeSigma | 1 min read
Discover how to obtain optimal PCR results by selecting the right DNA polymerase and optimizing the reaction buffer.
blind mole rat
Blind Mole Rats Use Junk DNA to Combat Cancer
Ruth Williams | Sep 30, 2021 | 3 min read
Activation of retrotransposons in the animals’ cancerous cells sets off an innate immune response that triggers cell death.
Abstract illustration of DNA
Signaling Dynamics Fine-Tune Gene Expression
Ruth Williams | Sep 3, 2021 | 3 min read
The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.
An immunoglobulin, also known as an antibody, floating in solution.
Shining a Light on Mass Photometry
The Scientist’s Creative Services Team and Refeyn | 3 min read
Mass photometry is an interferometric scattering-based technique offering researchers unprecedented characterization of biomolecular complexes and oligomerization in physiologically-relevant situations.
Illustration showing how yeast is used to study histone modifications
Infographic: A Yeast Model for Studying Histone Modifications
Amanda Heidt | Sep 1, 2021 | 1 min read
The methodology involves modifying histones and displaying them on the cell surface for analysis.
Saccharomyces cerevisiae yeast, 3D illustration. Microscopic fungi, baker's or brewer's yeast, are used as probiotics to restore normal flora of intestine
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Amanda Heidt | Sep 1, 2021 | 3 min read
By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.
Learn about hot topics in organoid research
Next-Level Organoids
The Scientist’s Creative Services Team | 1 min read
Researchers use organoid cultures in unique ways to study health and disease.
M. Mueckler looking at the camera in front of his microscope in 1998.
Cellular Biologist Michael Mueckler Dies at 67
Lisa Winter | Aug 18, 2021 | 1 min read
His work centered on the mechanisms of glucose transport into cells.
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