Two agar plates next to each other. One is empty while the other is growing multiple different cultured organisms, colored white, beige, and green.
Most Archaea and Bacteria Are Nameless. SeqCode Could Change That
The Scientist spoke with microbiologist William Whitman about a new system of nomenclature for prokaryotic organisms that can’t be cultured.
Most Archaea and Bacteria Are Nameless. SeqCode Could Change That
Most Archaea and Bacteria Are Nameless. SeqCode Could Change That

The Scientist spoke with microbiologist William Whitman about a new system of nomenclature for prokaryotic organisms that can’t be cultured.

The Scientist spoke with microbiologist William Whitman about a new system of nomenclature for prokaryotic organisms that can’t be cultured.

molecular biology
3D rendering of a scanning electron micrograph of pink malignant cancer cells against a black background
Cancers Ramp Up Overall mRNA Expression as They Progress
Dan Robitzski | Jun 14, 2022
A technique for quantifying tumor mRNA production from messy tissue sample data uncovers an unexpected correlation between it and disease stage in 15 cancer types.
An illustration showing a scale weighing two double-stranded pieces of DNA that has a big question mark in the center.
Mouse Foraging Behavior Shaped by Opposite-Sex Parent’s Genes
Dan Robitzski | Apr 12, 2022
A study in mice finds that for certain genes, one parent’s allele can dominate expression and shape behavior—and which parent’s allele does so varies throughout the body.
stock photo
Cooking up the Perfect PCR Reaction
MilliporeSigma
Discover how to obtain optimal PCR results by selecting the right DNA polymerase and optimizing the reaction buffer.
Deborah Nickerson
Genome Pioneer Deborah Nickerson Dies at 67
Amanda Heidt | Feb 9, 2022
The University of Washington researcher leveraged data from the Human Genome Project to identify genes underlying various health conditions and advance precision medicine.
Donald Caspar smiling into camera holding a buckyball model
Legendary Crystallographer Donald Caspar Dies At 94
Lisa Winter | Jan 7, 2022
He coined the term “structural biology.”
An immunoglobulin, also known as an antibody, floating in solution.
Shining a Light on Mass Photometry
The Scientist Creative Services Team and Refeyn
Mass photometry is an interferometric scattering-based technique offering researchers unprecedented characterization of biomolecular complexes and oligomerization in physiologically-relevant situations.
A notecard with outdated names of prokaryotic phyla crossed out and replaced with the newer names.
Newly Renamed Prokaryote Phyla Cause Uproar
Dan Robitzski | Jan 4, 2022
The International Committee on Systematics of Prokaryotes recently pulled the rank of phylum into its code of official nomenclature. Experts say the move will help standardize science in the long run but potentially disrupt research now.
An illustration of a yeast cell (right) and a human neuron (left) showing the processes/features that are similar in the two
Infographic: Modeling Neurodegenerative Diseases with Yeast
Mahlon Collins | Oct 1, 2021
Conservation of structures and functions between single-celled fungi and human cells allow researchers to probe the brain.
Learn about hot topics in organoid research
Next-Level Organoids
The Scientist Creative Services Team
Researchers use organoid cultures in unique ways to study health and disease.
Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.
blind mole rat
Blind Mole Rats Use Junk DNA to Combat Cancer
Ruth Williams | Sep 30, 2021
Activation of retrotransposons in the animals’ cancerous cells sets off an innate immune response that triggers cell death.
Streamline qPCR for Better Data
Streamlining qPCR Through Standardization
The Scientist Creative Services Team and Bio-Rad Laboratories
The importance of standardization for research and diagnostic result reproducibility
Abstract illustration of DNA
Signaling Dynamics Fine-Tune Gene Expression
Ruth Williams | Sep 3, 2021
The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.
Illustration showing how yeast is used to study histone modifications
Infographic: A Yeast Model for Studying Histone Modifications
Amanda Heidt | Sep 1, 2021
The methodology involves modifying histones and displaying them on the cell surface for analysis.
Improve qPCR Efficiency and Reproducibility
The Components of Effective qPCR
The Scientist Creative Services Team and Bio-Rad Laboratories
Putting the pieces together for molecular diagnostics and infectious disease research
Saccharomyces cerevisiae yeast, 3D illustration. Microscopic fungi, baker's or brewer's yeast, are used as probiotics to restore normal flora of intestine
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Amanda Heidt | Sep 1, 2021
By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.
M. Mueckler looking at the camera in front of his microscope in 1998.
Cellular Biologist Michael Mueckler Dies at 67
Lisa Winter | Aug 18, 2021
His work centered on the mechanisms of glucose transport into cells.
Millipore stock
Viral Nucleic Acid Purification in a Single Spin
The Scientist Creative Services Team and MilliporeSigma
A simple nucleic acid extraction approach quickly purifies genomic viral RNA and DNA while minimizing cross-contamination risks.
An illustration of an orange bacteriophage virus sitting on top of a green bacterium
Some Viruses Use an Alternative Genetic Alphabet
Abby Olena | Apr 29, 2021
In a trio of studies, researchers follow up on a 40-year-old finding that certain bacteriophages replace adenine with so-called diaminopurine, perhaps to avoid host degradation.