An illustration showing a scale weighing two double-stranded pieces of DNA that has a big question mark in the center.
Mouse Foraging Behavior Shaped by Opposite-Sex Parent’s Genes
A study in mice finds that for certain genes, one parent’s allele can dominate expression and shape behavior—and which parent’s allele does so varies throughout the body.
ABOVE: © ISTOCK.COM, BSD555
Mouse Foraging Behavior Shaped by Opposite-Sex Parent’s Genes
Mouse Foraging Behavior Shaped by Opposite-Sex Parent’s Genes

A study in mice finds that for certain genes, one parent’s allele can dominate expression and shape behavior—and which parent’s allele does so varies throughout the body.

A study in mice finds that for certain genes, one parent’s allele can dominate expression and shape behavior—and which parent’s allele does so varies throughout the body.

ABOVE: © ISTOCK.COM, BSD555

molecular biology

Deborah Nickerson
Genome Pioneer Deborah Nickerson Dies at 67
Amanda Heidt | Feb 9, 2022
The University of Washington researcher leveraged data from the Human Genome Project to identify genes underlying various health conditions and advance precision medicine.
Donald Caspar smiling into camera holding a buckyball model
Legendary Crystallographer Donald Caspar Dies At 94
Lisa Winter | Jan 7, 2022
He coined the term “structural biology.”
Streamline qPCR for Better Data
Streamlining qPCR Through Standardization
The Scientist Creative Services Team, Bio-Rad Laboratories | May 4, 2022
The importance of standardization for research and diagnostic result reproducibility
A notecard with outdated names of prokaryotic phyla crossed out and replaced with the newer names.
Newly Renamed Prokaryote Phyla Cause Uproar
Dan Robitzski | Jan 4, 2022
The International Committee on Systematics of Prokaryotes recently pulled the rank of phylum into its code of official nomenclature. Experts say the move will help standardize science in the long run but potentially disrupt research now.
An illustration of a yeast cell (right) and a human neuron (left) showing the processes/features that are similar in the two
Infographic: Modeling Neurodegenerative Diseases with Yeast
Mahlon Collins | Oct 1, 2021
Conservation of structures and functions between single-celled fungi and human cells allow researchers to probe the brain.
Improve qPCR Efficiency and Reproducibility
The Components of Effective qPCR
The Scientist Creative Services Team, Bio-Rad Laboratories | Apr 18, 2022
Putting the pieces together for molecular diagnostics and infectious disease research
Scanning electron micrograph (SEM) of the unicellular yeast Saccharomyces cerevisiae, known as Baker's or Brewer's yeast.
Yeast Models Provide New Insights into Neurodegenerative Diseases
Mahlon Collins | Oct 1, 2021
The single-celled fungus allows researchers to study Alzheimer’s, Parkinson’s, ALS and other brain diseases with unparalleled speed and scale.
blind mole rat
Blind Mole Rats Use Junk DNA to Combat Cancer
Ruth Williams | Sep 30, 2021
Activation of retrotransposons in the animals’ cancerous cells sets off an innate immune response that triggers cell death.
Millipore stock
Viral Nucleic Acid Purification in a Single Spin
The Scientist Creative Services Team, MilliporeSigma | Apr 6, 2022
A simple nucleic acid extraction approach quickly purifies genomic viral RNA and DNA while minimizing cross-contamination risks.
Abstract illustration of DNA
Signaling Dynamics Fine-Tune Gene Expression
Ruth Williams | Sep 3, 2021
The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.
Illustration showing how yeast is used to study histone modifications
Infographic: A Yeast Model for Studying Histone Modifications
Amanda Heidt | Sep 1, 2021
The methodology involves modifying histones and displaying them on the cell surface for analysis.
The Influence of Rare Cells in the Nervous System
The Influence of Rare Cells in the Nervous System
The Scientist Creative Services Team | Jan 6, 2022
Sebastian Lewandowski and Philip Hasel will discuss using single-cell techniques to understand the role of rare cell subtypes in neuroinflammation and neurodegeneration.
Saccharomyces cerevisiae yeast, 3D illustration. Microscopic fungi, baker's or brewer's yeast, are used as probiotics to restore normal flora of intestine
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Amanda Heidt | Sep 1, 2021
By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.
M. Mueckler looking at the camera in front of his microscope in 1998.
Cellular Biologist Michael Mueckler Dies at 67
Lisa Winter | Aug 18, 2021
His work centered on the mechanisms of glucose transport into cells.
Melissa Vos discusses how lipids’ good intentions become harmful in Parkinson’s Disease
The Scientist Speaks - Lipids Predict a Slippery Path Towards Parkinson’s Disease
Nele Haelterman, PhD | Dec 14, 2021
Melissa Vos discusses how lipids’ good intentions become harmful in Parkinson’s Disease.
An illustration of an orange bacteriophage virus sitting on top of a green bacterium
Some Viruses Use an Alternative Genetic Alphabet
Abby Olena | Apr 29, 2021
In a trio of studies, researchers follow up on a 40-year-old finding that certain bacteriophages replace adenine with so-called diaminopurine, perhaps to avoid host degradation.
hiit high intensity interval training exercise histamine receptor fexofenadine ranitidine famotidine h1 h2 receptor
Regular HIIT Exercise Enhances Health via Histamine
Rachael Moeller Gorman | Apr 21, 2021
Men given high doses of two antihistamine drugs did not experience the same benefits of high intensity interval training that men on a placebo enjoyed, revealing some of the molecular underpinnings of exercise’s effect.
800x560 thumbnail image
Using Digital Spatial Profiling for Transcriptomic Analysis of Neuronal Subpopulations
The Scientist Creative Services Team in collaboration with Advanced Cell Diagnostics | Nov 12, 2021
Kit Fuhrman and Anushka Dikshit present how to obtain whole transcriptome data from spatially mapped neuron populations.
How a Centipede Survives its Own Species’ Venom
Shawna Williams | Nov 1, 2020
The same toxin targets different receptors in prey and conspecifics to deliver either a lethal or non-lethal blow.