Signaling Dynamics Fine-Tune Gene Expression
Signaling Dynamics Fine-Tune Gene Expression
The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.
Signaling Dynamics Fine-Tune Gene Expression
Signaling Dynamics Fine-Tune Gene Expression

The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.

The dynamic behavior of a transcriptional activator can be used to specify the activity level of its target gene, a study suggests.

molecular biology
Infographic: A Yeast Model for Studying Histone Modifications
Infographic: A Yeast Model for Studying Histone Modifications
Amanda Heidt | Sep 1, 2021
The methodology involves modifying histones and displaying them on the cell surface for analysis.
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Yeast “Mini Labs” Help Researchers Probe Histone Modifications
Amanda Heidt | Sep 1, 2021
By harnessing a unique property of yeast, scientists can synthesize histones and the enzymes that modify these proteins, which spool DNA and influence gene expression.
Cellular Biologist Michael Mueckler Dies at 67
Cellular Biologist Michael Mueckler Dies at 67
Lisa Winter | Aug 18, 2021
His work centered on the mechanisms of glucose transport into cells.
Some Viruses Use an Alternative Genetic Alphabet
Some Viruses Use an Alternative Genetic Alphabet
Abby Olena | Apr 29, 2021
In a trio of studies, researchers follow up on a 40-year-old finding that certain bacteriophages replace adenine with so-called diaminopurine, perhaps to avoid host degradation.
Regular HIIT Exercise Enhances Health via Histamine
Regular HIIT Exercise Enhances Health via Histamine
Rachael Moeller Gorman | Apr 21, 2021
Men given high doses of two antihistamine drugs did not experience the same benefits of high intensity interval training that men on a placebo enjoyed, revealing some of the molecular underpinnings of exercise’s effect.
How a Centipede Survives its Own Species’ Venom
How a Centipede Survives its Own Species’ Venom
Shawna Williams | Nov 1, 2020
The same toxin targets different receptors in prey and conspecifics to deliver either a lethal or non-lethal blow.
Molecular Biologist Jeff McKnight Dies at 36
Molecular Biologist Jeff McKnight Dies at 36
Amanda Heidt | Oct 8, 2020
The University of Oregon scientist studied the structure and function of chromatin, with the intent of designing new therapeutic tools.
For the Greater Good: A Profile of Eva Harris
For the Greater Good: A Profile of Eva Harris
Diana Kwon | Jul 13, 2020
Through groundbreaking studies on dengue and efforts to build scientific infrastructure in Latin America, the University of California, Berkeley, professor has bridged research with its benefits to society.
Infographic: Synthetases and the Evolution of Circulatory Systems
Infographic: Synthetases and the Evolution of Circulatory Systems
Amber Dance | Jun 1, 2020
Aminoacyl tRNA synthetases picked up new protein domains that participate in vasculature formation around the same time that organisms evolved key adaptations in the circulatory system.
Protein Synthesis Enzymes Have Evolved Additional Jobs
Protein Synthesis Enzymes Have Evolved Additional Jobs
Amber Dance | Jun 1, 2020
Aminoacyl-tRNA synthetases, which help translate the genetic code into protein, also function in angiogenesis, fat metabolism, and more.
Scientists Clone SARS-CoV-2 Genome with Quick Yeast-Based Method
Scientists Clone SARS-CoV-2 Genome with Quick Yeast-Based Method
Ruth Williams | May 6, 2020
The use of yeast artificial chromosomes has enabled the rapid genetic reconstruction of the novel coronavirus.
Colon Cancer Uses a Regenerative Playbook to Metastasize
Colon Cancer Uses a Regenerative Playbook to Metastasize
Shawna Williams | Apr 1, 2020
A study finds similarities between cells that heal wounds and those that lead deadly cancerous invasions.
Faulty Antibodies Undermine Widespread Research
Faulty Antibodies Undermine Widespread Research
Ruth Williams | Jan 30, 2020
Two papers reveal that many commonly used research antibodies don’t bind as believed, highlighting the need to validate these reagents before use.