Alzheimer’s Should be Characterized by Biomarkers: Report
Diana Kwon | Apr 10, 2018
A proposed definition of the disease emphasizes signs of neurodegeneration and the presence of β-amyloid and tau, rather than cognitive symptoms.
U.S. Air Force photo illustration, Chris McCann
Exosomes in Blood Indicate Mild TBI: Study
Exosomes in Blood Indicate Mild TBI: Study
Levels of tau, amyloid-β 42, and IL-10 extracted from extracellular vesicles that started out in the brain were higher in military personal suffering head injuries compared with healthy soldiers.
Levels of tau, amyloid-β 42, and IL-10 extracted from extracellular vesicles that started out in the brain were higher in military personal suffering head injuries compared with healthy soldiers.
Tau Production Increased in Alzheimer’s Patients
Jim Daley | Mar 21, 2018
The findings suggest that faster synthesis, rather than decreased clearance, causes the protein to build up in neurons.
Image of the Day: Unseen Trauma
The Scientist Staff | Jun 20, 2017
Pressure from simulated blast waves, similar to those generated by explosives, induced molecular markers of stress and injury within mouse retinas.
Speaking of Neuroscience
Jef Akst, Mary Beth Aberlin | Nov 18, 2016
A selection of notable quotes from the annual Society for Neuroscience meeting
Toward an Immunotherapy for Alzheimer’s Disease
Tanya Lewis | Jul 28, 2016
Targeting tau antibodies does not require effector function, researchers report.
Tangle Trigger
Jyoti Madhusoodanan | Jan 1, 2015
An enzyme that cleaves tau protein in acidic cellular conditions may trigger early events in Alzheimer’s disease.
The Scientist on The Pulse #1
Kerry Grens | Dec 13, 2013
Kerry Grens updates the latest science news for December 13, 2013
Tau Ligand Reveals Tangles In Vivo
Kerry Grens | Sep 18, 2013
In living humans, researchers image snarls of tau, one of the proteins associated with Alzheimer's disease.
Ready for Prime Time
Dennis J. Selkoe and John C. Morris | Feb 1, 2012
Biomarkers of Alzheimer’s disease are ready for widespread use in clinical trials.