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A Brush with Inheritance, 1878
Catherine Offord | Feb 1, 2018
Lampbrush chromosomes, first observed in the 19th century, still offer an unparalleled glimpse into how genetic information is organized in the cell.
Paused RNA Polymerase Quashes New Initiation of Transcription
Shawna Williams | Oct 1, 2017
Pauses may help cells fine-tune gene expression.
The Role of DNA Base Modifications
Skirmantas Kriaucionis | Sep 1, 2017
Researchers are just beginning to scratch the surface of how several newly recognized epigenetic changes function in the genome.
Infographic: The Various Forms of Methylated DNA
Skirmantas Kriaucionis | Aug 31, 2017
To expand the basic nucleotide alphabet, many species modify their DNA with epigenetic marks.
The RNA Age: A Primer
Ruth Williams | May 11, 2017
Our guide to all known forms of RNA, from cis-NAT to vault RNA and everything in between.
Noncoding RNA Helps Cells Recover from DNA Damage
Diana Kwon | May 1, 2017
Scientists discover transcripts from the same gene that can express both proteins and noncoding RNA.
Starvation Response Triggers Melanoma Invasion
Catherine Offord | Apr 1, 2017
Through similar mechanisms, amino acid depletion in culture and cytokine activity in the tumor microenvironment prompt cancer cells to metastasize.
Monitoring Post-Mortem Gene Transcription in Mice and Zebrafish
Joshua A. Krisch | Jan 26, 2017
Genes linked to embryonic development, stress, and cancer are increasingly transcribed into RNA after these animals die.
Infographic: Examining Open Chromatin
Ruth Williams | Dec 31, 2016
See how researchers visualize regions of active genes.
Nuclear Pores Come into Sharper Focus
André Hoelz, Daniel H. Lin | Dec 1, 2016
Solving a long-standing structural puzzle will open the door to understanding one of the cell’s most enigmatic machines.