Left-Handed DNA Has a Biological Role Within a Dynamic Genetic Code
Left-Handed DNA Has a Biological Role Within a Dynamic Genetic Code
Once considered an unimportant curiosity, Z-DNA is now recognized to provide an on-the-fly mechanism to regulate how an RNA transcript is edited.
Left-Handed DNA Has a Biological Role Within a Dynamic Genetic Code
Left-Handed DNA Has a Biological Role Within a Dynamic Genetic Code

Once considered an unimportant curiosity, Z-DNA is now recognized to provide an on-the-fly mechanism to regulate how an RNA transcript is edited.

Once considered an unimportant curiosity, Z-DNA is now recognized to provide an on-the-fly mechanism to regulate how an RNA transcript is edited.

transcription
Infographic: DNA Isn’t Always Right-Handed
Infographic: DNA Isn’t Always Right-Handed
Rachel Brazil | Jun 1, 2020
When the nucleic acid spirals to the left, it takes on a zig-zag shape known as Z-DNA that appears to regulate RNA editing.
Moderna’s Coronavirus Vaccine Spurs Immune Response: Early Data
Moderna’s Coronavirus Vaccine Spurs Immune Response: Early Data
Ashley Yeager | May 18, 2020
A clinical trial of the shot in eight volunteers suggests that it is safe and that it generates antibodies that neutralize SARS-CoV-2, but further testing is needed, scientists say.
DNA Damage Linked to Brain Overgrowth in Autism
DNA Damage Linked to Brain Overgrowth in Autism
Abby Olena | Feb 5, 2020
Cell lines from individuals with macrocephalic autism spectrum disorder have an increased number of double-strand breaks in the DNA of long neural genes.
Alternative Splicing Provides a Broad Menu of Proteins for Cells
Alternative Splicing Provides a Broad Menu of Proteins for Cells
Gabrielle M. Gentile, Hannah J. Wiedner, Emma R. Hinkle, and Jimena Giudice | Jan 13, 2020
It’s now clear that gene transcripts can be constructed in various ways, yet many questions remain about the process.
Technical Bias Widespread in RNA-Seq Datasets
Technical Bias Widespread in RNA-Seq Datasets
Diana Kwon | Nov 21, 2019
Genes that are exceptionally long or short are overrepresented in some published reports, which can lead to misinterpreted results.
What Does It Look Like to “Turn On” a Gene?
What Does It Look Like to “Turn On” a Gene?
Alla Katsnelson, Casey Rentz, Knowable Magazine | May 3, 2019
Only recently have scientists directly witnessed this most pivotal of events in biology, thanks to new technology that allows them to observe the process in living cells. It’s teaching them a lot.
A New Role for Yeast Introns: Helping Cells Cope Under Stress
A New Role for Yeast Introns: Helping Cells Cope Under Stress
Katarina Zimmer | Jan 16, 2019
Two studies contest the idea that the noncoding sequences are just “junk DNA,” demonstrating that they play important roles in the regulation of cell growth.
Genetic Neurologist: A Profile of Huda Zoghbi
Genetic Neurologist: A Profile of Huda Zoghbi
Anna Azvolinsky | Oct 31, 2018
Turning to molecular genetics, the Baylor pediatric neurologist and geneticist works to discover the biological basis for the rare neurological diseases she sees in her patients.
A Brush with Inheritance, 1878
A Brush with Inheritance, 1878
Catherine Offord | Jan 31, 2018
Lampbrush chromosomes, first observed in the 19th century, still offer an unparalleled glimpse into how genetic information is organized in the cell.