An electron microscope image of a sponge used for lentivirus transduction.

| 2 min read

A Sponge Can Simplify Lentivirus Transduction

Sponge pores can mimic microfluidics, placing cells and virus particles in close proximity to increase transduction efficiency.

Close-up of 8-channel pipette adding solution to a multi-well plate for transfection.

| 1 min read

Channeling Transfection Success and Enhanced Electroporation

Improving Gene Therapy Safety with Antibiotic- and Supplement-Free Mini Plasmids

Available on Demand

Improving Gene Therapy Safety with Antibiotic- and Supplement-Free Mini Plasmids

transfection

A digital graphic rendering of multiple DNA double helices on a white background.

Targeted Gene Integration for High-Throughput Applications

Nathan Ni, PhD | | 4 min read

Conceptual colorful illustration of scientists working with bioreactors and other laboratory equipment.

Next-Level Adeno-Associated Virus (AAV) Production

Available on Demand

iStock

Hijacking Viruses: Optimizing Lentivirus-Based Cell Engineering

The Scientist | | 1 min read

Learn What to Keep in Mind When Creating Transgenic Rodent Models

Designing Transgenic Rodent Models: Key Considerations

Taconic | | 1 min read

Cell division abstract image

Versatile and Sustainable: Cell Counting for the 21^st Century

DeNovix Inc.andThe Scientist | | 3 min read

Discover How to Verify Plasmid Quality with the Agilent Fragment Analyzer System

Analyzing Plasmids with Automated Electrophoresis

Agilent | | 1 min read

Learn How Researchers Make the Most of Viral Vectors for Gene Therapy

Viral Vector Platforms for Gene Therapy

The Scientist | | 1 min read

Learn how to develop robust cell therapy workflows

Non-viral Transfection for Cell Therapy and Beyond

Thermo Fisher Scientific | | 1 min read

How to Produce Successful Viral Vectors

How to Produce Successful Viral Vectors

Available on Demand

Learn about establishing a Gene Therapy Manufacturing Strategy

Considerations for Gene Therapy Manufacturing Strategies

Thermo Fisher Scientific | | 1 min read

Fluorescent microscopy images of cells after being transfected.

Universal Transfection Reagents: Improving Efficiency and Decreasing Cell Toxicity

Roche,MilliporeSigmaandThe Scientist | | 4 min read

To flag neurons that have experienced genotoxic stress, researchers developed an in vivo sensor using an adeno-associated viral vector, called PRISM. Because a cell’s DNA damage response (DDR)—which activates in response to stressors such as environmental toxins or the buildup of misfolded proteins—also responds to invading pathogens, PRISM has an easier time transfecting cells whose damage response mechanisms are preoccupied with existing DNA damage. Once inside, the virus hijacks the neuron’s DNA replication machinery, which reverts an engineered frameshift mutation in the virus and thereby prompts the production of a fluorescent protein that can be observed via microscopy.

Infographic: DNA Damage Viewed with Unprecedented Clarity

Amanda Heidt | | 2 min read

Broken DNA

DNA Damage Viewed with Unprecedented Clarity

Amanda Heidt | | 3 min read

Discover how innovation boosts clinical manufacturing efficiency

Innovating Cell Therapy

Thermo Fisher Scientific | | 1 min read

3d render illustration of Single strand ribonucleic acid.

Message in a Bottle: Developing mRNA Therapeutics

Mirus BioandThe Scientist | | 3 min read

Learn how to develop robust cell therapy workflows

A Faster, Scalable Electroporation System for Cell Therapies

Thermo Fisher Scientific | | 1 min read

Technique Talk: Cell Transfection Techniques

Technique Talk: Cell Transfection Techniques

Available on Demand

800x560-thermo-october

A Scalable Process to Efficiently Manufacture Adeno-Associated Viral Vectors

Thermo Fisher ScientificandThe Scientist | | 3 min read

Identifying Antibodies that Target Membrane Proteins in Their Native Conformations

OXGENEandThe Scientist | | 2 min read

Securing the Antibody Supply Chain through Recombinant Antibody Technology: A COVID-19 Case Study

Available on Demand

Page 1 of 2 - 32 Total Items

Trending

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

Photo of a woman submerged in icy water with her head and clasped hands above water.

What are the Risks and Benefits of a Cold Plunge?

Cold-water immersion enthusiasts tout its benefits for their health and wellbeing, but is it backed by scientific evidence?

An illustration of mustard-colored mitochondria against a dark blue background.

Mitochondrial DNA: A Maternal Legacy That Helps Trace the Past and Diagnose the Future

The mitochondrial genome can help researchers map ancestry and better understand the inheritance of mitochondrial diseases.

A woman eating chocolate.

Why Do Some Women Crave Chocolate Before Their Period?

A combination of hormones and neurotransmitter interactions contributes to sweet cravings during the premenstrual phase.

Multimedia

Graphic of silver and gold 3D spheres levitating in space

Transform Omics Workflows with Scalable Cell Prep

Levitation-based cell enrichment streamlines workflows and enhances reproducibility.

Conceptual image of genomic analysis showing multicolored DNA base sequences depicted as the letters C, G, A, and T.

Accelerating Cancer Research Through Comprehensive Genomic Analysis

Learn how the latest technology helps researchers overcome cancer research challenges.

May digest 2025 cover

May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

View this Issue

Research Resources

Podcasts

Webinars

Videos

Infographics

eBooks

iStock

TaqMan Probe & Assays: Unveil What's Possible Together

Fuel your research with our high-quality TaqMan™ Assays and probes. Experience unmatched performance, reliability, and detailed support tailored to your scientific needs. Click to explore our comprehensive coverage options now!

Meet Aunty and Tackle Protein Stability Questions in Research and Development

Meet Aunty and Tackle Protein Stability Questions in Research and Development

In this webinar, Andre Mueller will introduce Aunty, the latest tool that scientists use for rapid, high-resolution protein stability testing.

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

In this webinar, Nathan Sepulveda will share how to specifically and reproducibly measure residual HEK293 DNA during biotherapeutic product development.

How technology makes PCR instruments easier to use.

Making Real-Time PCR More Straightforward

Today’s thermocyclers are more intuitive and flexible, letting scientists focus on their experiments rather than their instruments.

Products

Product News

The Scientist Placeholder Image

Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

Long-lasting, bright F-actin staining made easy with Biotium's new ActinBrite™ High Affinity Phalloidin Conjugates.

Latest AI software simplifies image analysis and speeds up insights for scientists

The Aivia 15 release includes deep learning-powered tools for 2D and 3D cell segmentation.

BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours

The integrated solution enables parallel high-resolution analysis of hundreds to thousands of individual cells, addressing growing demand for scalable, multiomics approaches in single-cell research.

iStock

Agilent BioTek Cytation C10 Confocal Imaging Reader

From confocal, widefield, and live cell imaging to multimode reading, the Agilent BioTek Cytation C10 confocal imaging reader delivers crisp, high-resolution images and the ability to image and analyze 3D samples.