The ease of use and robustness of CRISPR-Cas technology revolutionized genome editing for research ranging from fundamental science to translational medicine. Initial successes inspired scientists to discover and create new CRISPR systems, including those using Cas9, Cas12, Cascade-Cas3, and Cas13 orthologues. In addition to targeting DNA, researchers developed next-generation CRISPR-Cas systems for RNA targeting, epigenetic modifications, and chromatin interactions, advancing research, medicine, and diagnostics.

Download this poster from The Scientist to learn about the next generation of CRISPR-Cas systems, how they improve biological understanding, and how they propel gene and cell therapy research.

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