Image of the Day: Gene-Edited Reptiles
Nicoletta Lanese | Sep 4, 2019
Scientists injected unfertilized anole lizard eggs with CRISPR-Cas9 to produce albino offspring.
Timing and Order of Molecular Events Recorded in Live Cells’ DNA
Timing and Order of Molecular Events Recorded in Live Cells’ DNA
Genetic engineers have co-opted base editing machinery to enable information storage and processing in the DNA of bacterial and mammalian cells.
Genetic engineers have co-opted base editing machinery to enable information storage and processing in the DNA of bacterial and mammalian cells.
Researchers Launch First Study of In Vivo CRISPR Therapy in Humans
Catherine Offord | Jul 26, 2019
A trial is recruiting patients to test the gene-editing technology’s ability to treat an inherited form of blindness caused by a mutation in the CEP290 gene.
US Senators Call for International Guidelines for Germline Editing
Jef Akst | Jul 16, 2019
In the wake of reports of CRISPRed babies born in China, a bipartisan resolution “opposes the experiments that resulted in pregnancies using genome-edited human embryos.”
USPTO Restarts CRISPR Patent Dispute Between Broad and UC
Jef Akst | Jun 26, 2019
The US patent office declares an interference between the intellectual property held by the Broad Institute and several patent applications filed by the University of California—opposite its previous ruling.
Fertility Clinics Sought Advice from Scientist Who CRISPRed Babies
Chia-Yi Hou | May 29, 2019
Emails reveal that a facility in Dubai and others have asked geneticist He Jiankui for help in gene-editing embryos.
Infographic: AI Predicts Post-CRISPR Repairs
Ashley Yeager | May 1, 2019
Double-strand breaks can produce several different outcomes.
Could AI Make Gene Editing More Accurate?
Ashley Yeager | May 1, 2019
Machine learning algorithms predict the repairs made to DNA after Cas9 cuts.
Mice Gene-Edited While Still in the Womb
Chia-Yi Hou | Apr 19, 2019
CRISPR reagents injected into the amniotic fluid inactivated a gene in the fetuses that would normally cause lung disease and kill the mice a few hours after birth.
Base Editors Cause Off-Target Mutations in RNA
Catherine Offord | Apr 18, 2019
A new study indicates that the modified CRISPR-Cas9 technology will need to be further refined before it can safely be used for research and therapeutic applications.