Illustration of two TALENs bound to DNA. Repetitive helices wrap around DNA and bind at dedicated sites in each repeat. An enzymatic nuclease domain attached to each TALEN allows for cutting of one strand of the DNA.

| 10 min read

A Tale of How TALENs Launched the Genome Editing Revolution

Researchers transformed a plant pathogen weapon into a programmable tool for DNA editing.

| 1 min read

Scaling Lentiviral Vector Manufacturing for Optimal Productivity

3D illustration of a tumor on a black background. The tumor has recruited blood vessels to grow into it from a main artery running at the bottom of the photo. Around the tumor, purple, pink, and blue immune cells try to enter the tumor microenvironment but are stopped.

| 2 min read

Inducible CAR T Cells Target Solid Tumors Better

gene editing

A white laboratory mouse with its pups.

In a First, Mouse Pups with Two Dads Live to Adulthood

Sneha Khedkar | | 3 min read

istock

Reaching New Heights with Genetic Engineering Techniques

Thermo Fisher ScientificandThe Scientist | | 1 min read

Crystal structure of adeno-associated virus serotype 3B

A Deep Dive into Viral Vectors for Gene Therapy

PolyplusandThe Scientist | | 1 min read

Improving Gene Therapy Safety with Antibiotic- and Supplement-Free Mini Plasmids

Improving Gene Therapy Safety with Antibiotic- and Supplement-Free Mini Plasmids

Available on Demand

Blue and pink DNA helix and human lungs on a blue background.

Nanoparticles Breathe New Life into Lungs

Sneha Khedkar | | 4 min read

Image of the small intestines and colon within a person with three circular callouts, highlighting different microbes.

Unlocking the Human Microbiome Mysteries: From Cancer to COVID-19

Laura Tran, PhD | | 4 min read

A conceptual illustration of scissors, which represents a CRISPR-Cas9 complex, cutting a DNA molecule.

Cell Engineering 101: Editing with CRISPR

EditCo | | 1 min read

Two hands holding tweezers and dissecting single points in a DNA sequence.

From CRISPR to Prime Editing: The Evolution of the Genome Editing Revolution

Danielle Gerhard, PhD | | 5 min read

Optimizing Gene Editing Experimental Design

Optimizing Gene Editing Experimental Design

Available on Demand

Conceptual vector image of scientist engage in molecular biology research.

Helper Plasmids Lend a Hand to AAV Production

SartoriusandPolyplus | | 1 min read

Twist

Synthetic Screens, Genes, and De Novo Proteins - A Special Podcast Series

Twist BioscienceandThe Scientist | | 2 min read

Dark blue RNA strands with a light blue background.

A CRISPR Tool for Tinkering with the Human Transcriptome

Danielle Gerhard, PhD | | 5 min read

Discover What Digital PCR Can Do Across a Wide Range of Applications

Digital PCR Applications

Thermo Fisher Scientific | | 1 min read

A digital graphic rendering of multiple DNA double helices on a white background.

Targeted Gene Integration for High-Throughput Applications

Nathan Ni, PhD | | 4 min read

Molecular illustration of CRISPR editing the DNA double helix

Prime Time Precision with CRISPR Technologies

The Scientist | | 1 min read

CRISPR Gene Drives and the Future of Evolution

Hannah Thomasy, PhD | | 10+ min read

All Roads Lead to Genome Editing

Danielle Gerhard, PhD | | 6 min read

Twisted DNA Increases CRISPR Off-target Effects

Shelby Bradford, PhD | | 4 min read

Avoiding Gene Editing’s Unintended Consequences

Tanvir Khan, PhD | | 4 min read

Conceptual vector illustration depicting CRISPR gene editing by scientists for medical applications.

Optimizing Gene Editing with PARP1 CRISPR Plasmids

Santa Cruz Biotechnology, Inc. andThe Scientist | | 3 min read

Page 1 of 11 - 202 Total Items

Trending

Photo of John Calhoun crouches within his rodent utopia-turned-dystopia

Universe 25 Experiment

A series of rodent experiments showed that even with abundant food and water, personal space is essential to prevent societal collapse, but Universe 25's relevance to humans remains disputed.

A red male cardinal and a brownish female sit on a branch in front of a green background.

Sex Determination: It’s in the Genes—Sometimes

Animals across the tree of life have developed a mind-boggling variety of ways to become male or female.

A group of large animals, some of which are being studied for cancer resistance genes and proteins, are pictured, including a bison, an elephant, a giraffe, a manatee, a zebra, and a whale.

Peto’s Paradox: How Gigantic Species Evolved to Beat Cancer

Scientists dive into the genomes of whales, elephants, and other animal giants looking for new weapons in the fight against cancer.

A cross-section of a mouse brain with staining for NOVA1 and cell nuclei.

Strange Squeaks: A Uniquely Human Gene Alters Mouse “Songs”

A human-specific NOVA1 variant changed mouse vocalizations, potentially providing insights into the evolution of language.

Multimedia

Discover the history, mechanics, and potential of PCR.

Become a PCR Pro

Learn how mastering the ins and outs of PCR can accelerate workflows and improve data.

Understanding Disease Through Biomarkers

Understanding Disease Through Biomarkers

Learn how scientists identify and characterize biomarkers for cancer, neurodegenerative diseases, and autoimmune disorders.

A greyscale image of cells dividing.

March 2025, Issue 1

How Do Embryos Know How Fast to Develop

In mammals, intracellular clocks begin to tick within days of fertilization.

View this Issue

Research Resources

Podcasts

Webinars

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Infographics

eBooks

Discover the history, mechanics, and potential of PCR.

Become a PCR Pro

Learn how mastering the ins and outs of PCR can accelerate workflows and improve data.

Explore polypharmacology’s beneficial role in target-based drug discovery

Embracing Polypharmacology for Multipurpose Drug Targeting

Polypharmacology allows scientists to explore novel therapeutic purposes for existing drugs and opens new doors to treat multifactorial diseases.

3D rendered cross section of influenza viruses, showing surface proteins on the outside and single stranded RNA inside the virus

Genetic Insights Break Infectious Pathogen Barriers

Molecular detection technologies help scientists rapidly and reliably find and address ever-evolving pathogens with optimal accuracy and sensitivity.

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Navigating Cold Storage Solutions

Discover the key features to consider when selecting a new refrigerator or freezer

Products

Product News

The Scientist Placeholder Image

Gilead’s Capsid Revolution Meets Our Capsid Solutions: Sino Biological – Engineering the Tools to Outsmart HIV

On February 18, 2025, Gilead Sciences announced a significant milestone: the U.S. FDA accepted their New Drug Applications (NDAs) for lenacapavir (LEN), a groundbreaking twice-yearly injectable HIV-1 capsid inhibitor for pre-exposure prophylaxis (PrEP).

Stirling Ultracold

Meet the Upright ULT Built for Faster Recovery - Stirling VAULT100™

Slow temperature recovery can threaten the integrity of your work. That’s Stirling Ultracold designed the VAULT100™ to operate at setpoints down to -100°C, so your samples may never be exposed to temperatures above -70°C during a typical door opening.

Chemidoc

ChemiDoc Go Imaging System

The next generation imager from the ChemiDoc Imaging System line. Effortlessly capture gel and western blot images from your benchtop without compromising on sensitivity and precision.

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Evotec Announces Key Progress in Neuroscience Collaboration with Bristol Myers Squibb

• Ongoing strategic partnership advances joint pipeline in neurodegeneration research
• Evotec receives a $20 million payment to further progress research

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