Researchers Uncover New Families of Gene-Editing Enzymes
Researchers Uncover New Families of Gene-Editing Enzymes
The results reveal evolutionary relatives of the Cas9 enzyme now used extensively in biotechnology.
Researchers Uncover New Families of Gene-Editing Enzymes
Researchers Uncover New Families of Gene-Editing Enzymes

The results reveal evolutionary relatives of the Cas9 enzyme now used extensively in biotechnology.

The results reveal evolutionary relatives of the Cas9 enzyme now used extensively in biotechnology.

gene editing
Book excerpt from <em>CRISPR People</em>
Book excerpt from CRISPR People
Henry T. Greely | Aug 1, 2021
In Chapter 6, author Henry T. Greely describes how news of the birth of gene-edited babies rocked a 2018 summit on human genome editing.
Opinion: How Biomedicine Could Transform Human Reproduction
Opinion: How Biomedicine Could Transform Human Reproduction
Henry T. Greely | Aug 1, 2021
CRISPR and other innovations are likely to open up a wealth of new options for how people have children.
WHO Releases New Recommendations on Human Genome Editing
WHO Releases New Recommendations on Human Genome Editing
Annie Melchor | Jul 12, 2021
The guidance comes after two years of consulting with hundreds of stakeholders, including indigenous peoples, religious leaders, patient groups, and scientists.
CRISPR&rsquo;s Adaptation to Genome Editing Earns Chemistry Nobel
CRISPR’s Adaptation to Genome Editing Earns Chemistry Nobel
Amanda Heidt | Oct 7, 2020
Emmanuelle Charpentier and Jennifer Doudna reprogrammed the bacterial immune response into one of the most popular tools for genetics and molecular biology.
Panel Lays Out Guidelines for CRISPR-Edited Human Embryos
Panel Lays Out Guidelines for CRISPR-Edited Human Embryos
Lisa Winter | Sep 4, 2020
The International Commission on the Clinical Use of Human Germline Genome Editing claims the technology is still too risky for therapeutic use.
New Gene Editing Tool Corrects Mutations in Mitochondrial DNA
New Gene Editing Tool Corrects Mutations in Mitochondrial DNA
Amanda Heidt | Jul 9, 2020
An enzyme pulled from toxic bacteria can enter the organelle and perform single-nucleotide DNA swaps.
Symptoms in ALS Mouse Model Improve with CRISPR Base Editing
Symptoms in ALS Mouse Model Improve with CRISPR Base Editing
Abby Olena | Apr 10, 2020
Researchers slowed disease progression in the mice by injecting two different viral vectors, each containing one part of the DNA encoding the Cas9 protein, to edit the causative gene.
First Patient Receives In Vivo CRISPR Editing
First Patient Receives In Vivo CRISPR Editing
Jef Akst | Mar 4, 2020
Doctors in Oregon delivered the gene editing machinery behind the retina in hopes of treating an inherited form of blindness, according to the companies that developed the therapy.
Infographic: A Gene Editor for Plant Mitochondrial DNA
Infographic: A Gene Editor for Plant Mitochondrial DNA
Ruth Williams | Mar 1, 2020
New TALEN-based tools enable the organelle’s genome to be targeted and modified.
Gene Editing Reaches Plant Mitochondria
Gene Editing Reaches Plant Mitochondria
Ruth Williams | Mar 1, 2020
Modified gene editing machinery enables targeted disruptions of mitochondrial genes in rice and rapeseed plants.
Image of the Day: Neural Branching Gene
Image of the Day: Neural Branching Gene
Emily Makowski | Jan 20, 2020
A gene involved in a newly described syndrome affects neural functioning in fruit fly embryos.
China Sentences Gene-Editing Scientist to Three Years in Jail
China Sentences Gene-Editing Scientist to Three Years in Jail
Emily Makowski | Dec 30, 2019
The modification of three babies’ genes by He Jiankui drew widespread criticism from scientists.
CRISPR-Edited T Cells Used in Cancer Patients for the First Time in the US
CRISPR-Edited T Cells Used in Cancer Patients for the First Time in the US
Emily Makowski | Nov 6, 2019
The initial findings from a small clinical trial of patients with multiple myeloma or sarcoma suggest that gene-edited immunotherapy is safe.
New &ldquo;Prime Editing&rdquo; Method Makes Only Single-Stranded DNA Cuts
New “Prime Editing” Method Makes Only Single-Stranded DNA Cuts
Emma Yasinski | Oct 21, 2019
In demonstrations in cell lines, the technique has a similar efficacy to CRISPR-Cas9, but fewer off-target effects.