An enzyme pulled from toxic bacteria can enter the organelle and perform single-nucleotide DNA swaps.

Researchers slowed disease progression in the mice by injecting two different viral vectors, each containing one part of the DNA encoding the Cas9 protein, to edit the causative gene.

Doctors in Oregon delivered the gene editing machinery behind the retina in hopes of treating an inherited form of blindness, according to the companies that developed the therapy.

New TALEN-based tools enable the organelle’s genome to be targeted and modified.

Modified gene editing machinery enables targeted disruptions of mitochondrial genes in rice and rapeseed plants.

A gene involved in a newly described syndrome affects neural functioning in fruit fly embryos.

The modification of three babies’ genes by He Jiankui drew widespread criticism from scientists.

The initial findings from a small clinical trial of patients with multiple myeloma or sarcoma suggest that gene-edited immunotherapy is safe.

In demonstrations in cell lines, the technique has a similar efficacy to CRISPR-Cas9, but fewer off-target effects.