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A close up of a tick held in a pair of forceps, with Kevin Esvelt’s face out of focus in the background.
CRISPR Gene Drives and the Future of Evolution
Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.
CRISPR Gene Drives and the Future of Evolution
CRISPR Gene Drives and the Future of Evolution

Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.

Genetic engineering pioneer Kevin Esvelt’s work highlights biotechnology’s immense potential for good—but also for catastrophe.

gene editing

All Roads Lead to Genome Editing
Danielle Gerhard, PhD | Feb 9, 2024 | 6 min read
Shondra Pruett-Miller has taken many paths in her career with her love of genome editing always as a guiding light.
Twisted DNA Increases CRISPR Off-target Effects
Shelby Bradford, PhD | Feb 8, 2024 | 4 min read
Understanding how Cas9 binds off-target sequences can help researchers refine CRISPR-mediated genome editing.
Conceptual vector illustration depicting CRISPR gene editing by scientists for medical applications.
Optimizing Gene Editing with PARP1 CRISPR Plasmids 
The Scientist and Santa Cruz Biotechnology, Inc. | 3 min read
CRISPR plasmids provide a robust solution for streamlining human cell transfection workflows.   
Avoiding Gene Editing’s Unintended Consequences
Tanvir Khan, PhD | Feb 2, 2024 | 4 min read
CRISPR-Cas9 editing leads to widespread loss of the targeted chromosome in human T cells, but scientists recently discovered a way to prevent such loss.
Blood vessel with flowing red blood cells and white immune cells.
New CRISPR Treatment Could Prevent HIV Reinfection after Viral DNA Excision
Jennifer Zieba, PhD | Aug 21, 2023 | 3 min read
Researchers design dual CRISPR treatments to remove HIV DNA and prevent reinfection in vitro.
Building Bridges podcast logo
Building Bridges for Translational Research - A Special Podcast Series
The Scientist and Cytiva | 2 min read
Translational scientists discuss their experiences taking preclinical concepts to the market.
Photo of Rosa Bacchetta, associate professor of pediatrics at Stanford University
The Future of Gene Therapy for a Rare Pediatric Autoimmune Disease
Niki Spahich, PhD | Jul 10, 2023 | 3 min read
By editing a mutated immune regulatory gene in patient cells, Rosa Bacchetta brings hope to those suffering from IPEX syndrome.
Scientist pipetting at the bench in white coat and purple gloves
Chek-Mate for Gliomas
Aparna Nathan, PhD | May 22, 2023 | 3 min read
New research may make immunotherapy possible for hard-to-treat brain tumors.
 Learn about analyzing mRNA with direct sequence mapping 
Solutions for mRNA Direct Sequence Mapping
Thermo Fisher Scientific | 1 min read
As mRNA therapeutics gain popularity, a novel solution for their development emerges.
Cas9 enzyme
Molecular Glue ‘Shreds’ Cas9 and Enables a New Form of CRISPR Control
Ida Emilie Steinmark, PhD | Apr 26, 2023 | 3 min read
In a bid to address safety concerns about immune reactions during treatment with CRISPR-based therapeutics, a new technique speeds up how quickly the body destroys the DNA-cutting enzyme Cas9.
Learn How Researchers Make the Most of Viral Vectors for Gene Therapy
Viral Vector Platforms for Gene Therapy
The Scientist | Feb 9, 2023 | 1 min read
In both the laboratory and clinic, scientists harness viral genetic transfer capabilities to develop gene therapies that modulate cellular function.
Learn How Cutting-Edge Science is Breaking Through Industry Barriers
Focus on Innovation: Scientific Advances Driving Biopharma Market Trends
The Scientist and Tecan | 1 min read
Explore the future of biopharma research and development.
Pseudomonas aeruginosa biofilm
Double Agents: Engineered Bacteria Tackle Pathogenic Biofilms in Mice
Katherine Irving | Jan 26, 2023 | 3 min read
Mycoplasma pneumoniae with pathogenic genes replaced by biofilm-degrading ones enhance survival in a mouse model of ventilator-associated pneumonia.
Illustration of DNA
Can “Gene Writing” Deliver What Gene Editing Can’t?
Dan Robitzski | Dec 12, 2022 | 10+ min read
A biotech startup called Tessera Therapeutics has made a splash with its claims about the trademarked technology. Is the excitement justified?
The Past, Present, and Future of Cell and Gene Therapy
The Past, Present, and Future of Cell and Gene Therapy
The Scientist and Bio-Rad Laboratories | 1 min read
Embark on the journey of cell and gene therapy—from its conception and development, to its present state, and into its future.
Lock and key illustration
Novel Yeast-Assembly Technique Yields Living Materials
Natalia Mesa, PhD | Nov 23, 2022 | 3 min read
Researchers say structures made of the cells could potentially be used to clean up uranium from oceans, heal wounds, and more.
Orange colony of bacteria on red medium
Skin Bacteria May Trigger Lupus: Mouse Study
Natalia Mesa, PhD | Oct 28, 2022 | 3 min read
Staphylococcus aureus appears to be the culprit.
Challenges and Applications
Combinatorial Single Cell CRISPR Screens: Challenges and Applications
The Scientist Creative Services Team in collaboration with 10x Genomics | 2 min read
An expert panel will discuss how single cell sequencing enhances throughput in CRISPR gene editing applications.
Karyotype with most chromosomes in blue, one in red and green. 
Researchers Fuse Mouse Chromosomes in Scientific First
Natalia Mesa, PhD | Aug 25, 2022 | 4 min read
The findings will likely help elucidate the effects of chromosome fusions, which can cause disease but have also contributed to evolution.
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