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pseudomonas aeruginosa biofilm
Double Agents: Engineered Bacteria Tackle Pathogenic Biofilms in Mice
Mycoplasma pneumoniae with pathogenic genes replaced by biofilm-degrading ones enhance survival in a mouse model of ventilator-associated pneumonia.
Double Agents: Engineered Bacteria Tackle Pathogenic Biofilms in Mice
Double Agents: Engineered Bacteria Tackle Pathogenic Biofilms in Mice

Mycoplasma pneumoniae with pathogenic genes replaced by biofilm-degrading ones enhance survival in a mouse model of ventilator-associated pneumonia.

Mycoplasma pneumoniae with pathogenic genes replaced by biofilm-degrading ones enhance survival in a mouse model of ventilator-associated pneumonia.

gene editing
Illustration of DNA
Can “Gene Writing” Deliver What Gene Editing Can’t?
Dan Robitzski | Dec 12, 2022 | 10+ min read
A biotech startup called Tessera Therapeutics has made a splash with its claims about the trademarked technology. Is the excitement justified?
Lock and key illustration
Novel Yeast-Assembly Technique Yields Living Materials
Natalia Mesa, PhD | Nov 23, 2022 | 3 min read
Researchers say structures made of the cells could potentially be used to clean up uranium from oceans, heal wounds, and more.
 Learn about analyzing mRNA with direct sequence mapping 
Solutions for mRNA Direct Sequence Mapping
Thermo Fisher Scientific | 1 min read
As mRNA therapeutics gain popularity, a novel solution for their development emerges.
Orange colony of bacteria on red medium
Skin Bacteria May Trigger Lupus: Mouse Study
Natalia Mesa, PhD | Oct 28, 2022 | 3 min read
Staphylococcus aureus appears to be the culprit.
Karyotype with most chromosomes in blue, one in red and green. 
Researchers Fuse Mouse Chromosomes in Scientific First
Natalia Mesa, PhD | Aug 25, 2022 | 4 min read
The findings will likely help elucidate the effects of chromosome fusions, which can cause disease but have also contributed to evolution.
Learn How Cutting-Edge Science is Breaking Through Industry Barriers
Focus on Innovation: Scientific Advances Driving Biopharma Market Trends
The Scientist Creative Services Team and Tecan | 1 min read
Explore the future of biopharma research and development.
A gloved hand holds a tweezer and pulls a section of DNA away from a double helix
First Person Dosed in Novel Gene Editing Clinical Trial
Amanda Heidt | Jul 12, 2022 | 4 min read
The biotech company Verve Therapeutics launched the study with the aim of using base editing to treat a genetic condition that causes high cholesterol and increases a person's risk of developing cardiovascular disease.
Green-tinged image of fly eye with shiny and black portions
New CRISPR Technique Causes Few Unintended Mutations in Fruit Flies
Jason P. Dinh | Jul 1, 2022 | 4 min read
A study finds that CRISPR-Nickase, which changes just one allele of a given gene, improves gene editing efficiency compared with CRISPR-Cas9.
The Past, Present, and Future of Cell and Gene Therapy
The Past, Present, and Future of Cell and Gene Therapy
The Scientist Creative Services Team and Bio-Rad Laboratories | 1 min read
Embark on the journey of cell and gene therapy—from its conception and development, to its present state, and into its future.
an artistic rendering of CRISPR/Cas9
Ten Years of CRISPR
Sophie Fessl, PhD | Jun 28, 2022 | 7 min read
This month marks ten years since CRISPR-Cas9 was repurposed as a gene editing system, so we’re looking back at what has been accomplished in a decade of CRISPR editing.
Two prime editing guide RNAs (pegRNAs), deliver Cas9 enzymes to targeted regions of the genome.
Infographic: Two Guide RNAs Make for Large, Stable Insertions
Dan Robitzski | Jun 13, 2022 | 1 min read
A new technique goes beyond CRISPR and writes two complementary strands of DNA directly into the genome.
Challenges and Applications
Combinatorial Single Cell CRISPR Screens: Challenges and Applications
The Scientist Creative Services Team in collaboration with 10x Genomics | 2 min read
An expert panel will discuss how single cell sequencing enhances throughput in CRISPR gene editing applications.
Genetic Syndrome and Genetic Disorder, 3D illustration of science concept.
With Two RNA Guides, Editing Technique Writes Long DNA Insertions
Dan Robitzski | Jun 13, 2022 | 3 min read
The approach, called GRAND, uses a second guide RNA to write complementary strands of DNA in targeted genomic locations, resulting in efficient insertions that can be hundreds of base pairs long.
A cockroach clings to the inside of a white mug.
Injecting Cockroaches with CRISPR Gene Edits Their Offspring
Sophie Fessl, PhD | May 25, 2022 | 4 min read
A new method has allowed researchers to conduct the first gene knock-out and knock-in edits on cockroaches and may extend to many other insects.
CRISPR for Genome Engineering in Drosophila
Technique Talk: CRISPR for Genome Engineering in Drosophila
The Scientist Creative Services Team | 1 min read
Discover how CRISPR is revolutionizing gene editing in a classic genetics research model.
Alcohol bottles at a bar
Epigenome Editing Decreases Alcohol Seeking and Anxiety in Rats
Natalia Mesa, PhD | May 20, 2022 | 4 min read
A CRISPR-based system that reverses epigenetic changes caused by adolescent binge drinking reduces adult addiction-like behaviors in rats, a study finds, suggesting that an epigenomic approach could someday help treat people with alcohol use disorder.
close-up of an Aedes aegypti mosquito on human skin
Researchers Discover What Attracts Mosquitoes to Humans
Sophie Fessl, PhD | May 11, 2022 | 5 min read
A brain area of Aedes aegypti responds specifically to components of human sebum, a study finds.
untitled-design
From Bench to Boardroom
Aparna Nathan | 5 min read
Taking inspiration from her PhD research, Ana Moreno formed a company where scientists use CRISPR to treat chronic pain
An orange CRISPR Cas 9 enzyme cutting DNA
CRISPR-Based Treatment Successfully Lowers Toxic Protein Levels
Natalia Mesa, PhD | Mar 2, 2022 | 3 min read
A first-of-its-kind gene therapy dramatically reduced misfolded protein levels in some clinical trial participants for up to six months and reduced levels in all participants for up to a year.
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