New TALEN-based tools enable the organelle’s genome to be targeted and modified.

Modified gene editing machinery enables targeted disruptions of mitochondrial genes in rice and rapeseed plants.

A gene involved in a newly described syndrome affects neural functioning in fruit fly embryos.

The modification of three babies’ genes by He Jiankui drew widespread criticism from scientists.

The initial findings from a small clinical trial of patients with multiple myeloma or sarcoma suggest that gene-edited immunotherapy is safe.

In demonstrations in cell lines, the technique has a similar efficacy to CRISPR-Cas9, but fewer off-target effects.

Genetically engineered Drosophila withstand toxins common in monarch butterflies’ diet.

The authors have requested a retraction of a paper that found people with the CCR5 Δ32 variant are more likely to die sooner.

Scientists injected unfertilized anole lizard eggs with CRISPR-Cas9 to produce albino offspring.