CRISPR-Edited T Cells Used in Cancer Patients for the First Time in the US
CRISPR-Edited T Cells Used in Cancer Patients for the First Time in the US
The initial findings from a small clinical trial of patients with multiple myeloma or sarcoma suggest that gene-edited immunotherapy is safe.
CRISPR-Edited T Cells Used in Cancer Patients for the First Time in the US
CRISPR-Edited T Cells Used in Cancer Patients for the First Time in the US

The initial findings from a small clinical trial of patients with multiple myeloma or sarcoma suggest that gene-edited immunotherapy is safe.

The initial findings from a small clinical trial of patients with multiple myeloma or sarcoma suggest that gene-edited immunotherapy is safe.

gene editing
New “Prime Editing” Method Makes Only Single-Stranded DNA Cuts
New “Prime Editing” Method Makes Only Single-Stranded DNA Cuts
Emma Yasinski | Oct 21, 2019
In demonstrations in cell lines, the technique has a similar efficacy to CRISPR-Cas9, but fewer off-target effects.
Image of the Day: Poison Tolerance
Image of the Day: Poison Tolerance
Emily Makowski | Oct 3, 2019
Genetically engineered Drosophila withstand toxins common in monarch butterflies’ diet.
Error in Study Linking HIV Resistance Gene to Increased Mortality
Error in Study Linking HIV Resistance Gene to Increased Mortality
Emily Makowski | Sep 30, 2019
The authors have requested a retraction of a paper that found people with the CCR5 Δ32 variant are more likely to die sooner.
Image of the Day: Gene-Edited Reptiles
Image of the Day: Gene-Edited Reptiles
Nicoletta Lanese | Sep 4, 2019
Scientists injected unfertilized anole lizard eggs with CRISPR-Cas9 to produce albino offspring.
Timing and Order of Molecular Events Recorded in Live Cells’ DNA
Timing and Order of Molecular Events Recorded in Live Cells’ DNA
Ruth Williams | Aug 22, 2019
Genetic engineers have co-opted base editing machinery to enable information storage and processing in the DNA of bacterial and mammalian cells.
Researchers Launch First Study of In Vivo CRISPR Therapy in Humans
Researchers Launch First Study of In Vivo CRISPR Therapy in Humans
Catherine Offord | Jul 26, 2019
A trial is recruiting patients to test the gene-editing technology’s ability to treat an inherited form of blindness caused by a mutation in the CEP290 gene.
US Senators Call for International Guidelines for Germline Editing
US Senators Call for International Guidelines for Germline Editing
Jef Akst | Jul 16, 2019
In the wake of reports of CRISPRed babies born in China, a bipartisan resolution “opposes the experiments that resulted in pregnancies using genome-edited human embryos.”
USPTO Restarts CRISPR Patent Dispute Between Broad and UC
USPTO Restarts CRISPR Patent Dispute Between Broad and UC
Jef Akst | Jun 26, 2019
The US patent office declares an interference between the intellectual property held by the Broad Institute and several patent applications filed by the University of California—opposite its previous ruling.
Fertility Clinics Sought Advice from Scientist Who CRISPRed Babies
Fertility Clinics Sought Advice from Scientist Who CRISPRed Babies
Chia-Yi Hou | May 29, 2019
Emails reveal that a facility in Dubai and others have asked geneticist He Jiankui for help in gene-editing embryos.