Symptoms in ALS Mouse Model Improve with CRISPR Base Editing
Symptoms in ALS Mouse Model Improve with CRISPR Base Editing
Researchers slowed disease progression in the mice by injecting two different viral vectors, each containing one part of the DNA encoding the Cas9 protein, to edit the causative gene.
Symptoms in ALS Mouse Model Improve with CRISPR Base Editing
Symptoms in ALS Mouse Model Improve with CRISPR Base Editing

Researchers slowed disease progression in the mice by injecting two different viral vectors, each containing one part of the DNA encoding the Cas9 protein, to edit the causative gene.

Researchers slowed disease progression in the mice by injecting two different viral vectors, each containing one part of the DNA encoding the Cas9 protein, to edit the causative gene.

gene editing
First Patient Receives In Vivo CRISPR Editing
First Patient Receives In Vivo CRISPR Editing
Jef Akst | Mar 4, 2020
Doctors in Oregon delivered the gene editing machinery behind the retina in hopes of treating an inherited form of blindness, according to the companies that developed the therapy.
Infographic: A Gene Editor for Plant Mitochondrial DNA
Infographic: A Gene Editor for Plant Mitochondrial DNA
Ruth Williams | Mar 1, 2020
New TALEN-based tools enable the organelle’s genome to be targeted and modified.
Gene Editing Reaches Plant Mitochondria
Gene Editing Reaches Plant Mitochondria
Ruth Williams | Mar 1, 2020
Modified gene editing machinery enables targeted disruptions of mitochondrial genes in rice and rapeseed plants.
Image of the Day: Neural Branching Gene
Image of the Day: Neural Branching Gene
Emily Makowski | Jan 20, 2020
A gene involved in a newly described syndrome affects neural functioning in fruit fly embryos.
China Sentences Gene-Editing Scientist to Three Years in Jail
China Sentences Gene-Editing Scientist to Three Years in Jail
Emily Makowski | Dec 30, 2019
The modification of three babies’ genes by He Jiankui drew widespread criticism from scientists.
CRISPR-Edited T Cells Used in Cancer Patients for the First Time in the US
CRISPR-Edited T Cells Used in Cancer Patients for the First Time in the US
Emily Makowski | Nov 6, 2019
The initial findings from a small clinical trial of patients with multiple myeloma or sarcoma suggest that gene-edited immunotherapy is safe.
New “Prime Editing” Method Makes Only Single-Stranded DNA Cuts
New “Prime Editing” Method Makes Only Single-Stranded DNA Cuts
Emma Yasinski | Oct 21, 2019
In demonstrations in cell lines, the technique has a similar efficacy to CRISPR-Cas9, but fewer off-target effects.
Image of the Day: Poison Tolerance
Image of the Day: Poison Tolerance
Emily Makowski | Oct 3, 2019
Genetically engineered Drosophila withstand toxins common in monarch butterflies’ diet.
Error in Study Linking HIV Resistance Gene to Increased Mortality
Error in Study Linking HIV Resistance Gene to Increased Mortality
Emily Makowski | Sep 30, 2019
The authors have requested a retraction of a paper that found people with the CCR5 Δ32 variant are more likely to die sooner.