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Infographic: Combo Method of Stem Cell Generation
Ruth Williams | Nov 30, 2017
Simultaneous exposure to reprogramming and gene-editing plasmids efficiently produces edited pluripotent colonies.
How Geneticists’ Views Compare to the Public’s on Genome Editing
Bob Grant | Oct 22, 2017
Professionals in the genetics field generally support editing the genomes of somatic cells, mirroring public opinion, but diverge from nonexperts when it comes to germline editing.
Gene Drive Limitations
Jef Akst | Oct 9, 2017
In lab populations of genetically engineered mosquitoes, mutations arose that blocked the gene drive’s spread and restored female fertility.
First CAR T-Cell Therapy Approved in U.S.
Shawna Williams | Aug 30, 2017
The genetically modified blood cells will be used for patients with a type of acute lymphoblastic leukemia, when other treatments fail.
Skin Graft-based Gene Therapy Treats Diabetes in Mice
Shawna Williams | Aug 4, 2017
A small patch of engineered cells makes an enzyme that stimulates insulin release.
Final Nail Hammered into NgAgo Coffin
Kerry Grens | Aug 3, 2017
The paper describing the gene-editing method is retracted.
Scientists Edit Viable Human Embryos in U.S.
Kerry Grens | Jul 27, 2017
The embryos, whose genes were altered by CRISPR, were not intended for implantation.
CRISPR Restores Muscle Function in Mice
Diana Kwon | Jul 17, 2017
Scientists use the gene-editing tool to treat animals with a rare form of congenital muscular dystrophy.
CRISPR Corrects Duchenne-Causing Mutations
Anna Azvolinsky | Apr 12, 2017
Using CRISPR-Cpf1 gene editing, researchers have fixed mutations that cause a form of muscular dystrophy in cultured human cardiomyocytes and a mouse model.
Massively Parallel Perturbations
Ruth Williams | Mar 1, 2017
Scientists combine CRISPR gene editing with single-cell sequencing for genotype-phenotype screens.