The Search for Immune Responses that Stop COVID-19

Scientists are examining the role of T cells, which are likely crucial for long-term protection against SARS-CoV-2.

Written byChris Baraniuk
| 5 min read
t cell b cell covid-19 coronavirus pandemic sars-cov-2 immune response innate immunity adaptive immunity antibodies antibody cd8+

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ABOVE: Antigen presenting cells (APCs) recruit T and B cells during a viral infection
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When COVID-19 began spreading like wildfire in the Northeast United States this spring, critical care doctor Nuala Meyer could barely believe what she was seeing.

“The number of patients who were presenting with critical illness all at the same time was staggering,” remembers Meyer, a professor of medicine at the Hospital of the University of Pennsylvania. But it wasn’t just that these patients were really sick—it was that they were sick in a startling variety of ways. Some had cardiac issues. Others had blood clots in their legs. Then there were those who developed pneumonia and related respiratory problems. Organ failure affected some. The list went on and on.

When Meyer and colleagues profiled the ways in ...

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  • chris baraniuk

    Chris Baraniuk is a freelance science journalist based in Northern Ireland who contributes to The Scientist. He has covered biological and medical science for a range of publications, including the BBC, the BMJ, and Mosaic. He also writes about nature, climate change, and technology. His background in the humanities has long proved invaluable in his quest to bring science stories to people from all walks of life.

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