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The Two Genomes in Every Eukaryotic Cell

Interactions between mitochondrial and nuclear genomes have further-reaching effects on physiological function, adaptation, and speciation than previously appreciated.

Written byViviane Callier
| 14 min read

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ABOVE: © SCIENCE PHOTO LIBRARY, sciepro

From Alaska down to the Baja Peninsula, the rocky tide pools of North America’s West Coast are separated by hundreds of kilometers of sandy beaches. Inside those tide pools live Tigriopus californicus copepods, small shrimp-like animals that evolutionary biologist Ron Burton has been studying since he was an undergraduate at Stanford University in the 1970s. During those early days of DNA technology, Burton became curious how the genomes of the isolated copepod populations compared.

While still at Stanford, Burton sequenced the mitochondrial gene cytochrome c oxidase subunit one, the standard marker people used at the time for species identification, and discovered that the copepod populations were strongly differentiated: on average, there was a 20 percent sequence divergence in this gene between populations. When he crossed Santa Cruz copepods with animals from San Diego, the hybrids did fine, but when he bred them to one ...

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Meet the Author

  • Viviane was a Churchill Scholar at the University of Cambridge, where she studied early tetrapods. Her PhD at Duke University focused on the role of oxygen in insect body size regulation. After a postdoctoral fellowship at Arizona State University, she became a science writer for federal agencies in the Washington, DC area. Now, she freelances from San Antonio, Texas.

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