Week in Review: February 24–28

New PLOS data sharing rules; mouse cortical connectome published; reprogramming astrocytes into neurons and fibroblasts into hepatocytes

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FLICKR, MISSERIONWhile the open-access publisher has always promoted data sharing, starting next week PLOS will require authors publishing in their journals to make the raw data behind the results freely available to all.

While many researchers applauded the publisher’s move, others questioned whether submitting authors would be willing to share such information, and at what cost.

“I wonder if most clinical investigators can do this feasibly,” noted Yale University cardiologist Harlan Krumholz. However, added The Cochrane Collaboration’s Tom Jefferson, an epidemiologist and a long-time clinical data-sharing advocate, “If people want to submit stuff for publication [to open-access journals], it’s absolutely right that they should make all the data available.”

CELL, ZINGG ET AL.Among the many ongoing efforts to fully map the mouse brain, a University of Southern California-led team has constructed a detailed connectome depicting the neuronal pathways of the murine cortex. The researchers published their work this week (February 27) in Cell and have made the mouse cortical connectome freely available online.

“The one thing I really appreciate about this work is that it combines the large data scale with careful, manual annotation and analysis of ...

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