Week in Review: November 2–6

How Ebola hides from immune cells; gut microbes’ role in immunotherapy response; new mechanisms of hearing loss; butterflies use milkweed toxins to ward off predators

Written byJef Akst
| 4 min read

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WIKIMEDIA, NEPHRONAfter an Ebola patient has recovered from the infection and her blood is virus-free, Ebola can still linger, hiding out—and sometimes replicating— for months in the immunoprivileged tissues of the body, including the eye, the placenta, and the brain.

“The only possible way that we could surmise that the virus could be present is that it was seeded from the acute original infection and persisted,” Daniel Bausch, who researches emerging pathogens at Tulane University in New Orleans and who worked with the World Health Organization (WHO) during the West African Ebola epidemic, told The Scientist. “We have very ample and increasing evidence that the virus can persist in some of these sites.”

Now researchers are trying to understand how Ebola survives in these tissues—and how to knock out the virus for good, though Bausch emphasizes that the evidence suggests Ebola will eventually disappear on its own. “It’s just that these are sites where it’s harder for your immune system to get into and so ...

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  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

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