Week in Review: September 16–20

Dealing with anonymous misconduct allegations; efficiently generating iPSCs; distinguishing viral infections from non-viral; imaging tau in vivo

Written byTracy Vence
| 3 min read

Register for free to listen to this article
Listen with Speechify
0:00
3:00
Share

WIKIMEDIA, FRANCESCO MIRALLES GALUPAn anonymous accusation of publishing foul play from whistleblower “Clare Francis” had the Mayo Clinic’s Michael Sarr chasing down a dead end this summer. Francis had alerted Sarr, who is editor of Surgery, to a potential case of dual publication involving his journal. But after thoroughly examining the papers in question, Sarr found no evidence of misconduct, and was left feeling that Francis had wasted his time.

Increasingly, scientists who wish to point out potential flaws in the published literature are doing so under a veil of anonymity. While Sarr’s experience points out the potential downside to not knowing whether the source is reliable, sometimes the criticisms are founded—leading to rightful corrections and retractions. Virginia Barbour, chair of the Committee on Publication Ethics (COPE), which offers advice to journal editors on how to handle misconduct, told The Scientist that whistleblowing “is about . . . trying to make sure the scientific literature is as robust as possible,” and as such, “it shouldn’t matter who it comes from.”

According to Retraction Watch blog co-founder Ivan Oranksy, “more and more journals are realizing the importance of every kind of whistleblower, anonymous or not.”

WIKIMEDIA, A. TANAKA ET AL.Researchers from Israel’s Weizmann Institute of Science have identified a single gene that seems to suppress pluripotency, and consequently, proposed in a report this week a way of producing induced pluripotent stem cells (iPSCs) with nearly 100 percent efficiency. Jacob Hanna and his colleagues found that by disabling Mdb3—or working with cells lacking the gene—they could reprogram blood and skin cells from mice, plus human skin cells, with almost complete efficiency and in just one week.

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

View this Issue
Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Beckman Coulter Logo
Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

bioxcell

Products

Sino Biological Logo

Sino Biological Pioneers Life Sciences Innovation with High-Quality Bioreagents on Inside Business Today with Bill and Guiliana Rancic

Sino Biological Logo

Sino Biological Expands Research Reagent Portfolio to Support Global Nipah Virus Vaccine and Diagnostic Development

Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

Refeyn logo

Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies