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The composition of gut microbes in babies born via Cesarean section tends to differ from those in babies born vaginally, prompting speculation that this may have long-term health consequences. To enrich for beneficial bugs in babies’ bellies after C-section, researchers have performed mom-to-infant microbial transplants, described today (October 1) in Cell. In a clinical trial in which seven Cesarean-delivered babies were fed tiny amounts of their mothers’ fecal material, it was found that the babies’ guts became colonized with the sorts of bacteria normally present in infants delivered vaginally. While the procedure produced no ill effects in the infants, there are no data on whether it has any benefits to the baby, and experts warn it may be dangerous for mothers to attempt such a treatment themselves.
“This is a very well-balanced, important, and clinically relevant contribution to the field, with really nice, clear-cut conclusions,” says ...