Giant Viruses Can Integrate into the Genomes of Their Hosts

Rather than introducing small chunks of DNA as other viruses do, some giant viruses can contribute more than 1 million base pairs to a host’s genome, broadening the ways in which viruses may shape eukaryote evolution.

Written byAmanda Heidt

| 4 min read

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green algae, phytoplankton, giant virus, genetics & genomics, endogenization, evolution, diversity, eukaryote

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ABOVE: Scientists have found evidence that giant viruses integrate their genomes into that of their hosts, such as this species of Chlorella, a single-celled green algae.
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In the ultimate game of genetic hide and seek, scientists at Virginia Tech have identified several instances in which they found giant virus genomes embedded—some in their entirety—in the genomes of their hosts. The results, published today (November 18) in Nature, suggest that such integration by giant viruses may be more common than previously believed and that these viruses are likely an underappreciated source of genetic diversity in eukaryotes.

“We always assumed that [giant viruses] that can integrate into host genomes were not common,” Karen Weynberg, a virologist at the University of Queensland in Australia who was not involved in the work, tells The Scientist. “Now they’ve shown that these viruses are able to integrate on a much wider scope than we ever ...

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Meet the Author

Amanda Heidt
Amanda first began dabbling in scicom as a master’s student studying marine science at Moss Landing Marine Labs, where she edited the student blog and interned at a local NPR station. She enjoyed that process of demystifying science so much that after receiving her degree in 2019, she went straight into a second master’s program in science communication at the University of California, Santa Cruz. Formerly an intern at The Scientist, Amanda joined the team as a staff reporter and editor in 2021 and oversaw the publication’s internship program, assigned and edited the Foundations, Scientist to Watch, and Short Lit columns, and contributed original reporting across the publication. Amanda’s stories often focus on issues of equity and representation in academia, and she brings this same commitment to DEI to the Science Writers Association of the Rocky Mountains and to the board of the National Association of Science Writers, which she has served on since 2022. She is currently based in the outdoor playground that is Moab, Utah. Read more of her work at www.amandaheidt.com.
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