Researchers at the University of Texas at Austin captured the process in which developing killer T cells are tested by dendritic and others types of cells to see if they react to normal proteins from the body, called self-antigens. This safety check ensures that the T cells don’t harm normal cells in the body and cause autoimmune disorders.
J.N. Lancaster et al., “Live-cell imaging reveals the relative contributions of antigen-presenting cell subsets to thymic central tolerance,” Nature Communications, doi:10.1038/s41467-019-09727-4, 2019.
