In Search of the Best Milk Recipe for Preemies’ Gut Bacteria

Milk fortifiers of human origin show no evident advantage in the development of the gut microbiota of premature infants over fortifiers derived from cows, while the intake of the mother’s own milk does, two studies suggest.

Written byAlejandra Manjarrez, PhD
| 5 min read
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Premature newborns, otherwise known as preemies, face additional challenges in their first months of life as a result of missing out on the protection and nourishment they would otherwise get inside the womb. Many of these babies, for example, have higher nutritional requirements, for which human- or bovine-derived milk fortifiers (a more concentrated version of the formula given to term infants) are added to their primary source of milk, whether it is their mother’s or a donor’s. If they are mainly feeding on formula, they also get a more concentrated recipe designed for their condition.

Two independent studies—one published August 19 in Cell Host & Microbe and the other published August 26 in Cell Reports Medicine—assessed the role of these different dietary components in the development of the preemie gut microbiome. Their results suggest that there is no strong evidence that human-derived milk fortifiers are more advantageous than cows’ in ...

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  • alejandra manjarrez

    Alejandra Manjarrez is a freelance science journalist who contributes to The Scientist. She has a PhD in systems biology from ETH Zurich and a master’s in molecular biology from Utrecht University. After years studying bacteria in a lab, she now spends most of her days reading, writing, and hunting science stories, either while traveling or visiting random libraries around the world. Her work has also appeared in Hakai, The Atlantic, and Lab Times.

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