March 2018

The Transgender Brain

Researchers seek clues to the origins of gender dysphoria

Features

Paleoproteomics Opens a Window into the Past

Eat Yourself to Live: Autophagy’s Role in Health and Disease

Contributors

Contributors

Editorial

The Skin We’re In

Speaking of Science

Ten-Minute Sabbatical

Notebook

Study Finds Epigenetic Differences Between Hatchery-Raised and Wild-Born Salmon

UK Judges Receive Primers on Forensic Science

Could Rapamycin Help Humans Live Longer?

Stressed Rodents Make Different Choices

Modus Operandi

Here Comes Single-Cell Optogenetics

Cover Story

Are the Brains of Transgender People Different from Those of Cisgender People?

The Literature

Bacterial Cell Envelope Size is Key to Membrane Stress Response

Circulating Mitochondrial DNA Alerts Immune System to Danger

A Systematic Approach to Finding Unannotated Proteins

Profiles

Parasitologist, Reprogrammed: A Profile of David Roos

Scientist to Watch

Jermaine Jones Seeks to Untangle the Genetics Behind Substance Abuse

Lab Tools

New Methods to Detect CRISPR Off-Target Mutations

Careers

How to Successfully Collaborate with Industry

Reading Frames

The Forgotten History of World War I–Era Female Scientists

Foundations

The Child Hatchery, 1896

February 2026

A Stubborn Gene, a Failed Experiment, and a New Path

When experiments refuse to cooperate, you try again and again. For Rafael Najmanovich, the setbacks ultimately pushed him in a new direction.

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Human-Relevant In Vitro Models Enable Predictive Drug Discovery

Advancing Drug Discovery with Complex Human In Vitro Models

Stemcell Technologies
Redefining Immunology Through Advanced Technologies

Redefining Immunology Through Advanced Technologies

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

Ensuring Regulatory Compliance in AAV Manufacturing with Analytical Ultracentrifugation

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Conceptual multicolored vector image of cancer research, depicting various biomedical approaches to cancer therapy

Maximizing Cancer Research Model Systems

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Products

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Beckman Coulter

Beckman Coulter Life Sciences Partners with Automata to Accelerate AI-Ready Laboratory Automation

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Refeyn named in the Sunday Times 100 Tech list of the UK’s fastest-growing technology companies