PET Scans Reveal Elevated Tau in NFL Players’ Brains

A study hints that it might be possible to diagnose chronic traumatic encephalopathy, a neurodegenerative disease associated with frequent head injuries, while patients are still living.

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Researchers have found that tau protein levels detected on brain scans of living people may serve as a biomarker of chronic traumatic encephalopathy, a brain disease that has been linked to repeated head trauma. Although years off, a diagnostic that uses such biomarkers could give patients a warning about the associated cognitive, mood, and behavioral issues they may endure, and perhaps give doctors a chance to levy interventions to ward off the symptoms of CTE, which is currently only able to be diagnosed by brain examinations postmortem.

In a study published Wednesday (April 10) in the New England Journal of Medicine, researchers at Boston University, a leader in CTE research, used positron emission tomography (PET) scans to assess levels of the tau protein in 26 living former NFL players who have started to experience cognitive difficulties and in 31 similarly aged male controls. They found that ...

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Meet the Author

  • Jef Akst

    Jef Akst was managing editor of The Scientist, where she started as an intern in 2009 after receiving a master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses.
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