Q&A: Gathering Diverse Microbiome Samples

Cofounders of a microbiome biobank speak with The Scientist about their new partnership with nonprofit OpenBiome and how to ethically work with donors.

Written byKatherine Irving
| 8 min read
Matthieu Groussin sits with three other people on stools in front of a low table, on which there are several bowls of food. Another person stands above Groussin spooning something into a bowl.
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When microbiologist Mathilde Poyet and medical bioinformatician Mathieu Groussin first met as postdocs in Eric Alm’s microbiome lab at MIT in 2014, they realized two things. First, the lack of diversity in the microbiome data they were using made it nearly impossible for them to study anything but white people in industrialized communities, and therefore, the applicability of their work would be limited. Indeed, studies have found that data gathered from industrialized countries are unfit for creating therapies or microbiome-based treatments for use elsewhere. Second, they realized that they could do something about it.

Teaming up, the two embarked on a worldwide mission to recruit a greater variety of people to be represented in microbiome research. Groussin and Poyet have traveled to dozens of countries over the past six years to work with local scientists and communities, set up microbiome sample collections, and store them in a biobank. Their project ...

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    Katherine Irving is an intern at The Scientist. She studied creative writing, biology, and geology at Macalester College, where she honed her skills in journalism and podcast production and conducted research on dinosaur bones in Montana. Her work has previously been featured in Science.  

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