Q&A: Data Gaps Hinder Monitoring of SARS-COV-2 Variants

Martha Nelson of the National Institute of Allergy and Infectious Diseases talks about the need to balance data sharing and patient privacy concerns when tracking the spread of variants.

Written byJef Akst
| 6 min read

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Martha Nelson, a senior biologist in the Laboratory of Parasitic Diseases at the US National Institute of Allergy and Infectious Diseases, tracks variants of SARS-CoV-2 in as close to real time as possible. But linking viral genetic sequence data with details about the person that sample came from is often impossible, yet those details are crucial to understanding how the virus is spreading.

“It’s been painfully slow because there is no national system for data sharing and piles of red tape to get patient metadata needed to make a genetic sequence meaningful,” Nelson writes to The Scientist in an email. “The CDC has been leading efforts to get US sequencing higher in terms of volume, but the lack of coordination and sharing of data makes the information fragmented and hard to interpret.”

What would be ideal, she says, is marrying sequence data with contact tracing information, ...

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  • Jef (an unusual nickname for Jennifer) got her master’s degree from Indiana University in April 2009 studying the mating behavior of seahorses. After four years of diving off the Gulf Coast of Tampa and performing behavioral experiments at the Tennessee Aquarium in Chattanooga, she left research to pursue a career in science writing. As The Scientist's managing editor, Jef edited features and oversaw the production of the TS Digest and quarterly print magazine. In 2022, her feature on uterus transplantation earned first place in the trade category of the Awards for Excellence in Health Care Journalism. She is a member of the National Association of Science Writers.

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