Sex Promotes Lasting Memories in Female Flies

A protein present in the ejaculate of male fruit flies activates long-term memory formation in the brains of their female partners.

ruth williams
| 3 min read
fruit fly drosophila melanogaster sperm sex peptide memory reproduction

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After copulation, Drosophila melanogaster females are able to create long-term memories of unpleasant events—electric shocks—that virgin females cannot, according to a study published today in Science Advances (November 20). The authors suspect the memory boost may improve the chance of survival of the female during the subsequent egg-laying period as well as guide her choice of laying sites. Whatever the reason, the enhanced memory joins a list of physiological and behavioral effects on female flies that result from sex.

“It’s quite impressive and convincing [data],” says entomologist Elwyn Isaac of the University of Leeds who was not involved in the research. “They propose that the sex peptide gets into the [female’s] circulation and somehow gets across the blood brain barrier [to activate memory].”

It’s “very interesting,” Isaac continues, because until now, sex peptide—a protein produced in the male reproductive system and found in ejaculate—was thought to ...

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