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3D rendered image showing enhanced scanning electron micrograph of cancer cells
Turning Off Metastasis in Breast Cancer
An on-off enzyme switch controls metastasis in mice. 
Turning Off Metastasis in Breast Cancer
Turning Off Metastasis in Breast Cancer

An on-off enzyme switch controls metastasis in mice. 

An on-off enzyme switch controls metastasis in mice. 

cancer research

The Vaginal Microbiome is Finally Getting Recognized
Hannah Thomasy, PhD, Drug Discovery News | Sep 25, 2023 | 10+ min read
Vaginal dysbiosis has long been a taboo subject, but studying and optimizing the vaginal microbiome could be a game changer for women's health.
3D rendered medical illustration of T cells trying to subdue cancer cells.
How Tumors Tire Out T Cells
Bruker Cellular Analysis | Jul 19, 2023 | 1 min read
Researchers investigated how cancer antigenicity drives unique forms of T cell exhaustion and hypofunctionality.
Sino Biological 
CAR Technology in Cancer Therapy: From CAR-T to CAR-NK
The Scientist and Sino Biological | 4 min read
From early target discovery to preclinical development stages, researchers explore novel strategies for effective cell therapies in cancer treatment.
Tasmanian devil wrapped in blanket
Tasmanian Devils Face Threats from Rapidly Evolving Facial Cancers 
Natalia Mesa, PhD | Jun 30, 2023 | 3 min read
A genetic study tracked the evolution of two transmissible cancers currently ravaging populations of Tasmanian devils.
Green and brown illustration of cancer cells in front of a peach and yellow background.
Bacterial Tractor Beams Bring Radiation to Tumors
Rachael Moeller Gorman | Apr 17, 2023 | 3 min read
Colonizing tumors with engineered bacteria may allow researchers to target sites currently inaccessible to radionuclide therapy.
From histopathology to multiplex immunohistochemistry and spatial transcriptomics, learn how to obtain the appropriate profiling depth to match cancer classification needs.
Broadening Tumor Molecular Profiling Horizons
Canopy Biosciences | 1 min read
From histopathology to multiplex immunohistochemistry and spatial transcriptomics, learn how to obtain the appropriate profiling depth to match cancer classification needs.
illustration of cancer cells moving
Cancer Cells Gather Speed in Thicker Fluids
Holly Barker, PhD | Nov 22, 2022 | 4 min read
Viscous solutions accelerate the migration of tumor cells and may enable metastasis, according to a new study.
A purple-stained section of an invasive breast cancer growth. The dark purple non-fatty tissue takes up the majority of the frame, and pale purple circular tumors grow in ducts in the bottom left.
Harboring Hard and Soft Cells Lets Tumors Grow and Metastasize Simultaneously
Katherine Irving | Oct 17, 2022 | 4 min read
Islands of rigid cells within a matrix of soft ones allow tumors to be both solid and fluid, granting them toughness without losing the ability to break apart.
Human DNA stock photo
Setting Better Traps for PARP Inhibitors
The Scientist and BPS Bioscience | 4 min read
An innovative assay permits researchers to screen for small molecule PARP inhibitors that trap the enzyme on DNA and selectively execute cancer cells.
exterior of Fred Hutch research building
Fred Hutch Receives $710 Million Gift from the Bezos Family
Shawna Williams | Oct 13, 2022 | 1 min read
The donation will fund recruitment, research facilities, clinical research, and immunotherapy research.
illustration of blue cells with exosomes budding off of them and floating away
Nanoparticles Spur Mouse Immune System to Attack Cancer
Shafaq Zia | Sep 13, 2022 | 2 min read
A study finds that engineered exosomes are effective in mice, but their potential use in humans raises safety questions.  
Enhancing the Efficacy of CAR-T Cell Therapies
The Scientist Creative Services Team in Collaboration with IsoPlexis | 1 min read
Jessica Morris will discuss strategies to improve CAR-T cell targeting, activation, and killing capabilities.
woman smiling at camera
Renee Wegrzyn Tapped to Head ARPA-H
Andy Carstens | Sep 12, 2022 | 2 min read
As the new agency’s director, the DARPA veteran will spearhead a high-risk, high-reward approach to biomedical research.
Histological slide showing cancerous prostate tissue
2D Genetic Map of Prostate Cells Charts Cancer Growth
Holly Barker, PhD | Aug 23, 2022 | 4 min read
An in situ map of copy number variations in prostate tissue reveals that purportedly cancerous genomic changes frequently occur in the healthy tissue surrounding tumors.
Best of Cancer Research
The Scientist | 1 min read
This collection of articles from The Scientist explores some of the latest cancer research!
Monica Bertagnolli standing in a hallway
White House Names Monica Bertagnolli as NCI Director
Andy Carstens | Aug 10, 2022 | 2 min read
The announcement confirms earlier reports that Bertagnolli will become the first woman to lead the National Cancer Institute since its founding in 1937.
black-and-white brain scan showing tumor
Glioblastoma Cells Imitate Immature Neurons to Invade the Brain
Sophie Fessl, PhD | Aug 5, 2022 | 3 min read
Neuron-like glioblastoma cells are the pioneers of deadly tumors’ spread through the brain, contributing to their devastating invasiveness, a study in mice finds.
Genetic and Spatial Heterogeneity in Human Papillomavirus-Associated Oropharyngeal Cancer
The Scientist | 1 min read
Joseph Powell will discuss how heterogeneous subpopulations of HPV+ head and neck cancer cells drive unique disease states, cell-cell interactions, and microenvironment dynamics, and have implications for cancer behavior, metastasis, and response to treatment.   
Artist’s 3D rendering of malignant cancer cells, illustrated in pink, as it would appear under a scanning electron microscope.
Underdog Enzyme Likely Responsible for Mutations in Most Cancers
Sophie Fessl, PhD | Jul 28, 2022 | 3 min read
A previously overlooked enzyme called APOBEC3A is linked to the most prevalent mutational signatures in cancer cell lines, a study finds.
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