Cancer Cells Could Travel Through the Interstitium: Study
Cancer Cells Could Travel Through the Interstitium: Study
The continuous network of fluid-filled compartments crosses organ barriers and might serve as a conduit for tumor cells to spread.
Cancer Cells Could Travel Through the Interstitium: Study
Cancer Cells Could Travel Through the Interstitium: Study

The continuous network of fluid-filled compartments crosses organ barriers and might serve as a conduit for tumor cells to spread.

The continuous network of fluid-filled compartments crosses organ barriers and might serve as a conduit for tumor cells to spread.

macrophage
Microscopic Robots Deliver Drugs to the Brain
Microscopic Robots Deliver Drugs to the Brain
Asher Jones | Mar 30, 2021
Researchers turned white blood cells called neutrophils into drug-smuggling “neutrobots,” which penetrated the blood-brain barrier to treat brain cancer in mice.
CAR Macrophages Tackle Challenges in Solid Cancer Treatment
CAR Macrophages Tackle Challenges in Solid Cancer Treatment
Amanda Heidt | Mar 26, 2021
Following on the success of CAR T cells used to treat cancers of the blood, researchers have launched a Phase 1 clinical trial of genetically modified macrophages to target solid tumors.
Understanding Transplant Rejection with Single-Cell Proteomics
Understanding Transplant Rejection with Single-Cell Proteomics
The Scientist Creative Services Team | Mar 9, 2021
Researchers find key drivers of allograft rejection!
Infographic: Envisioning Macrophages
Infographic: Envisioning Macrophages
Ashley Yeager | Mar 1, 2021
Researchers find different distributions of the immune cells in young, older, and diseased eyes.
Macrophages of the Human Eye Come into Focus
Macrophages of the Human Eye Come into Focus
Ashley Yeager | Mar 1, 2021
Imaged in real time in living people, immune cells at the surface of the retina could serve as biomarkers to detect retinal and possibly neurological diseases and track their progression.
A Tweak to Immune Cells Reverses Aging in Mice
A Tweak to Immune Cells Reverses Aging in Mice
Abby Olena | Jan 20, 2021
Knocking out the receptor for a lipid that causes inflammation rejuvenates macrophage metabolism and restores cognitive function in an Alzheimer’s disease model.
Investigating the Immune Response Using Advanced Flow Cytometry
Investigating the Immune Response Using Advanced Flow Cytometry
The Scientist Creative Services Team | Oct 8, 2020
Discover how researchers are using flow cytometry to delve into the inner workings of the immune life cycle!
Is a Bradykinin Storm Brewing in COVID-19?
Is a Bradykinin Storm Brewing in COVID-19?
Alakananda Dasgupta | Aug 26, 2020
Excess of the inflammatory molecule bradykinin may explain the fluid build-up in the lungs of patients with coronavirus infections. Clinical trials of inhibitors are putting this hypothesis to the test.
Infographic: SARS-CoV-2 Interferes with Bradykinin Regulation
Infographic: SARS-CoV-2 Interferes with Bradykinin Regulation
Alakananda Dasgupta | Aug 26, 2020
The leaky blood vessels and lung fluid build-up in some COVID-19 patients might be explained by the virus’s corruption of an inflammation safeguard.
An Old TB Vaccine Finds New Life in Coronavirus Trials
An Old TB Vaccine Finds New Life in Coronavirus Trials
Anthony King | May 4, 2020
Studies are underway to test whether giving a shot of BCG vaccine could protect doctors and nurses against COVID-19.
Image of the Day: Brainless Frogs
Image of the Day: Brainless Frogs
Amy Schleunes | Feb 18, 2020
Without a brain, the frog embryo immune system doesn’t receive the signals it needs to mobilize macrophages and fight infections.
Side Effect of CAR T Therapy Caused by Pyroptosis: Mouse Study
Side Effect of CAR T Therapy Caused by Pyroptosis: Mouse Study
Kerry Grens | Jan 20, 2020
The immunotherapy induces a form of cell death in leukemia cells in mice that triggers cytokine release syndrome, a dangerous inflammatory reaction that occurs in some patients.
Mitochondria Play an Unexpected Role in Killing Bacteria
Mitochondria Play an Unexpected Role in Killing Bacteria
Katarina Zimmer | Jan 1, 2019
The energy-producing organelles also send out parcels with antimicrobial compounds to help destroy pathogen invaders in macrophages.
Macrophages Play a Double Role in Cancer
Macrophages Play a Double Role in Cancer
Amanda B. Keener | Apr 1, 2018
Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.
Hungry Macrophages Keep Tattoos on Mice’s Skin
Hungry Macrophages Keep Tattoos on Mice’s Skin
Diana Kwon | Mar 7, 2018
A new study reveals that a constant stream of ink-gobbling immune cells helps hold tattoos in place.
Glial Ties to Persistent Pain
Glial Ties to Persistent Pain
Mark R. Hutchinson | Jan 1, 2018
Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.
Infographic: Two Pain Paths Diverge in the Body
Infographic: Two Pain Paths Diverge in the Body
Mark R. Hutchinson | Dec 31, 2017
The acute pain that results from injury or disease is very different from chronic pain.
Macrophages Are the Ultimate Multitaskers
Macrophages Are the Ultimate Multitaskers
Claire Asher | Oct 1, 2017
From guiding branching neurons in the developing brain to maintaining a healthy heartbeat, there seems to be no job that the immune cells can’t tackle.
Infographic: Macrophages Around the Body
Infographic: Macrophages Around the Body
Claire Asher | Sep 30, 2017
In addition to circulating in the blood as immune sentinels, macrophages play specialized roles in different organs around the body.