Is a Bradykinin Storm Brewing in COVID-19?
Is a Bradykinin Storm Brewing in COVID-19?
Excess of the inflammatory molecule bradykinin may explain the fluid build-up in the lungs of patients with coronavirus infections. Clinical trials of inhibitors are putting this hypothesis to the test.
Is a Bradykinin Storm Brewing in COVID-19?
Is a Bradykinin Storm Brewing in COVID-19?

Excess of the inflammatory molecule bradykinin may explain the fluid build-up in the lungs of patients with coronavirus infections. Clinical trials of inhibitors are putting this hypothesis to the test.

Excess of the inflammatory molecule bradykinin may explain the fluid build-up in the lungs of patients with coronavirus infections. Clinical trials of inhibitors are putting this hypothesis to the test.

macrophage
Investigating the Immune Response Using Advanced Flow Cytometry
Investigating the Immune Response Using Advanced Flow Cytometry
The Scientist Creative Services Team | Oct 8, 2020
Discover how researchers are using flow cytometry to delve into the inner workings of the immune life cycle!
Infographic: SARS-CoV-2 Interferes with Bradykinin Regulation
Infographic: SARS-CoV-2 Interferes with Bradykinin Regulation
Alakananda Dasgupta | Aug 26, 2020
The leaky blood vessels and lung fluid build-up in some COVID-19 patients might be explained by the virus’s corruption of an inflammation safeguard.
An Old TB Vaccine Finds New Life in Coronavirus Trials
An Old TB Vaccine Finds New Life in Coronavirus Trials
Anthony King | May 4, 2020
Studies are underway to test whether giving a shot of BCG vaccine could protect doctors and nurses against COVID-19.
Image of the Day: Brainless Frogs
Image of the Day: Brainless Frogs
Amy Schleunes | Feb 18, 2020
Without a brain, the frog embryo immune system doesn’t receive the signals it needs to mobilize macrophages and fight infections.
Side Effect of CAR T Therapy Caused by Pyroptosis: Mouse Study
Side Effect of CAR T Therapy Caused by Pyroptosis: Mouse Study
Kerry Grens | Jan 20, 2020
The immunotherapy induces a form of cell death in leukemia cells in mice that triggers cytokine release syndrome, a dangerous inflammatory reaction that occurs in some patients.
Mitochondria Play an Unexpected Role in Killing Bacteria
Mitochondria Play an Unexpected Role in Killing Bacteria
Katarina Zimmer | Dec 31, 2018
The energy-producing organelles also send out parcels with antimicrobial compounds to help destroy pathogen invaders in macrophages.
Macrophages Play a Double Role in Cancer
Macrophages Play a Double Role in Cancer
Amanda B. Keener | Mar 31, 2018
Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.
Hungry Macrophages Keep Tattoos on Mice’s Skin
Hungry Macrophages Keep Tattoos on Mice’s Skin
Diana Kwon | Mar 7, 2018
A new study reveals that a constant stream of ink-gobbling immune cells helps hold tattoos in place.
Glial Ties to Persistent Pain
Glial Ties to Persistent Pain
Mark R. Hutchinson | Dec 31, 2017
Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.