Without a brain, the frog embryo immune system doesn’t receive the signals it needs to mobilize macrophages and fight infections.

The immunotherapy induces a form of cell death in leukemia cells in mice that triggers cytokine release syndrome, a dangerous inflammatory reaction that occurs in some patients.

The energy-producing organelles also send out parcels with antimicrobial compounds to help destroy pathogen invaders in macrophages.

Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.

A new study reveals that a constant stream of ink-gobbling immune cells helps hold tattoos in place.

Immune-like cells in the central nervous system are now recognized as key participants in the creation and maintenance of persistent pain.

The acute pain that results from injury or disease is very different from chronic pain.

From guiding branching neurons in the developing brain to maintaining a healthy heartbeat, there seems to be no job that the immune cells can’t tackle.

In addition to circulating in the blood as immune sentinels, macrophages play specialized roles in different organs around the body.