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mRNA vaccine

SARS-CoV-2 self-assembling virus-like nanoparticle with spike proteins protruding from the surface.

New Technology Improves SARS-CoV-2 mRNA Vaccine-Induced Immune Responses

Elina Kadriu | May 30, 2023 | 3 min read

mRNA-encoded self-assembling enveloped virus-like particles presenting SARS-CoV-2 spike protein enhance immunity and may provide better protection against viral variants.

Four glass vials sit on a reflective tabletop next to a syringe. Each is labeled as a subsequent dose in a four-dose series of COVID-19 vaccines.

What We Know About Getting a Second Booster Shot of COVID-19 Vaccines

Dan Robitzski | Aug 11, 2022 | 10+ min read

Studies show that a fourth mRNA vaccine dose offers the elderly and other high-risk groups strong protection against hospitalization and death from COVID-19, but experts say benefits for other populations may be more limited.

Building Bridges for Translational Research - A Special Podcast Series

The Scientist’s Creative Services Team and Cytiva | 2 min read

Translational scientists discuss their experiences taking preclinical concepts to the market.

Brick building with tall windows and white letters out front that say "Food and Drug Administration"

FDA Limits Use of J&J Vaccine, Citing Safety Concerns

Natalia Mesa, PhD | May 6, 2022 | 2 min read

US adults are now only eligible for the vaccine under certain circumstances.

A masked doctor in a white coat and blue gloves administers a vaccine into the arm of a masked child.

Pfizer Vaccine Less Protective for Younger Kids: Preprint

Dan Robitzski | Feb 28, 2022 | 3 min read

The vaccine’s effectiveness in children ages 5 to 11 rapidly declined over the course of a month, according to new research that looked at the health outcomes of hundreds of thousands of children in New York during the Omicron surge.

3d render illustration of Single strand ribonucleic acid.

Message in a Bottle: Developing mRNA Therapeutics

The Scientist’s Creative Services Team and Mirus Bio | 3 min read

A high efficiency, low toxicity method for direct RNA delivery into cells.

Stethoscope on top of form and clipboard

Robert Malone Targets Physician Who Alerted Medical Board to Misinformation

Catherine Offord | Feb 19, 2022 | 8 min read

A Hawaii hospital worker who reported the controversial scientist to the Maryland Board of Physicians was subjected to harassment and a retaliatory complaint after Malone made his name and location public.

People waiting in line for COVID Vaccine

CDC: COVID-19 Booster Effectiveness Wanes After Four Months

Natalia Mesa, PhD | Feb 14, 2022 | 2 min read

The agency also finds that third shots prevented hospitalizations during the Omicron wave.

CAR T Cells Mend Broken Mouse Hearts

Sophie Fessl, PhD | Jan 6, 2022 | 4 min read

Specialized immune cells generated in vivo reduce cardiac scar tissue in mice, a new study shows.

Antibodies in breastmilk from SARS-CoV-2 infection or mRNA vaccination neutralize the virus.

Antibodies Against SARS-CoV-2 in Breast Milk Differ Between Vaccinated and Infected Mothers

Roni Dengler, PhD | Dec 6, 2021 | 3 min read

All antibodies against SARS-CoV-2 found in breast milk neutralized the virus.

black-legged deer tick waits on leaf for host to feed on

A Lab-Stage mRNA Vaccine Targeting Ticks May Offer Protection Against Lyme and Other Tick-Borne Diseases

Andaleeb Sajid | Nov 18, 2021 | 3 min read

NIH researcher Andaleeb Sajid discusses her study’s finding that ticks were unable to feed on vaccinated guinea pigs, preventing transmission of the pathogen that causes Lyme disease.

Can mRNA Vaccine Momentum Propel Tumor Immunotherapies?

Aparna Nathan, PhD | Nov 12, 2021 | 4 min read

A guide to mRNA-based cancer vaccines and where they’re headed next

cartoon image showing colorful collection of syringes, coronavirus particles, and mrna to represent the vaccine development

Optogenetics and mRNA Vaccines Net Lasker Awards

Annie Melchor | Sep 24, 2021 | 2 min read

This year’s winners are Dieter Oesterhelt, Peter Hegemann, Karl Deisseroth, Drew Weissman, Katalin Karikó, and David Baltimore.

Moderna vs. Pfizer: Is There a “Best” mRNA Vaccine?

Alejandra Manjarrez, PhD | Sep 24, 2021 | 10 min read

Both of the mRNA vaccines available in the US are highly effective against severe COVID-19, but recent studies suggest that Moderna’s elicits a stronger immune response and might be better at preventing breakthrough infections.

photograph of a syringe and vial of colorless liquid

FDA Approves Pfizer-BioNTech COVID-19 Vaccine

Annie Melchor | Aug 23, 2021 | 3 min read

The milestone marks the first fully-approved COVID-19 vaccine in the United States.

cartoon of a scientist holding a magnifying glass up to test tubes of blood

How the Second mRNA Vaccine Bolsters Immunity

Annie Melchor | Jul 23, 2021 | 6 min read

A study looks beyond T and B cell responses to show how the Pfizer COVID-19 vaccine elicits a strong innate immune response.

Illustration of the BCG vaccine and resulting immune response

Infographic: TB Vaccines in the Pipeline Take Varied Approaches

Anthony King | Jul 1, 2021 | 3 min read

More than a dozen vaccines for tuberculosis are currently being tested in clinical trials. Some use whole bacteria as BCG does, while others deliver protein subunits or genetic material carried by viral vectors.

False-colored micrograph of Mycobacterium tuberculosis

Tuberculosis: The Forgotten Pandemic

Anthony King | Jul 1, 2021 | 10+ min read

This month marks the 100-year anniversary of BCG, still the only approved vaccine against the lethal pathogen. But there are new vaccines for this wily foe on the horizon.

Woman holding a CDC COVID-19 vaccination card with both hands.

COVID-19 mRNA Vaccines Appear Effective Against Multiple Variants

Lisa Winter | May 6, 2021 | 2 min read

Data from three studies indicate that fully vaccinated patients are able to stave off severe disease from the B.1.1.7, B.1.351, and P.1 variants.