A digital rendering of Plasmodium trophozoite in red blood cells.
A New mRNA Malaria Vaccine 
By targeting resident memory T cells in the liver, a novel mRNA malaria vaccine prevented infection, even in those with prior exposure.
A New mRNA Malaria Vaccine 
A New mRNA Malaria Vaccine 

By targeting resident memory T cells in the liver, a novel mRNA malaria vaccine prevented infection, even in those with prior exposure.

By targeting resident memory T cells in the liver, a novel mRNA malaria vaccine prevented infection, even in those with prior exposure.

mRNA vaccine

A vial labeled “mRNA vaccine” and a syringe on a blue background.
An Updated Approach to mRNA Vaccine Quality Assessment
Deanna MacNeil, PhD | Nov 13, 2023 | 3 min read
Researchers developed and validated a sequencing method for mRNA vaccines, moving the manufacturing field forward by linking established technologies with translational applications.
A triangular sign affixed to a tree displaying the silhouette of a tick.
Newly Developed mRNA Vaccine Protects Against Lyme Disease
Charlene Lancaster, PhD | Nov 13, 2023 | 5 min read
Leveraging the same mRNA platform used for COVID-19 vaccines, researchers generated a vaccine that prevents mice from acquiring Lyme disease.
<em >The Scientist</em>&rsquo;s Journal Club: Infectious Diseases
The Scientist’s Journal Club: Infectious Diseases
The Scientist | 1 min read
Scientists present the latest research on infection prevention and treatment, including COVID-19 and tropical infectious diseases.
Black and gold sketch of Katalin Karik&oacute; and Drew Weissman.
Nobel Prize for mRNA Vaccines
Danielle Gerhard, PhD | Oct 2, 2023 | 5 min read
Katalin Karikó and Drew Weissman received this year’s Physiology or Medicine award for their work on RNA biology and mRNA-based vaccines.
SARS-CoV-2 self-assembling virus-like nanoparticle with spike proteins protruding from the surface.
New Technology Improves SARS-CoV-2 mRNA Vaccine-Induced Immune Responses
Elina Kadriu | May 30, 2023 | 3 min read
mRNA-encoded self-assembling enveloped virus-like particles presenting SARS-CoV-2 spike protein enhance immunity and may provide better protection against viral variants. 
Building Bridges podcast logo
Building Bridges for Translational Research - A Special Podcast Series
The Scientist and Cytiva | 2 min read
Translational scientists discuss their experiences taking preclinical concepts to the market.
RSV vaccine design concept art
RSV Vaccines That Work?
Rachael Moeller Gorman | Feb 16, 2023 | 10+ min read
Multiple candidates are in Phase 3 clinical trials for older adults and pregnant women, with some getting close to approval in the United States.
Four glass vials sit on a reflective tabletop next to a syringe. Each is labeled as a subsequent dose in a four-dose series of COVID-19 vaccines.
What We Know About Getting a Second Booster Shot of COVID-19 Vaccines
Dan Robitzski | Aug 11, 2022 | 10+ min read
Studies show that a fourth mRNA vaccine dose offers the elderly and other high-risk groups strong protection against hospitalization and death from COVID-19, but experts say benefits for other populations may be more limited.
3d render illustration of Single strand ribonucleic acid.
Message in a Bottle: Developing mRNA Therapeutics
The Scientist and Mirus Bio | 3 min read
A high efficiency, low toxicity method for direct RNA delivery into cells.
Brick building with tall windows and white letters out front that say "Food and Drug Administration"
FDA Limits Use of J&J Vaccine, Citing Safety Concerns
Natalia Mesa, PhD | May 6, 2022 | 2 min read
US adults are now only eligible for the vaccine under certain circumstances.
A masked doctor in a white coat and blue gloves administers a vaccine into the arm of a masked child.
Pfizer Vaccine Less Protective for Younger Kids: Preprint
Dan Robitzski | Feb 28, 2022 | 3 min read
The vaccine’s effectiveness in children ages 5 to 11 rapidly declined over the course of a month, according to new research that looked at the health outcomes of hundreds of thousands of children in New York during the Omicron surge.
Stethoscope on top of form and clipboard
Robert Malone Targets Physician Who Alerted Medical Board to Misinformation
Catherine Offord | Feb 19, 2022 | 8 min read
A Hawaii hospital worker who reported the controversial scientist to the Maryland Board of Physicians was subjected to harassment and a retaliatory complaint after Malone made his name and location public.
People waiting in line for COVID Vaccine
CDC: COVID-19 Booster Effectiveness Wanes After Four Months
Natalia Mesa, PhD | Feb 14, 2022 | 2 min read

The agency also finds that third shots prevented hospitalizations during the Omicron wave.

knitted pink heart with a mended hole
CAR T Cells Mend Broken Mouse Hearts
Sophie Fessl, PhD | Jan 6, 2022 | 4 min read
Specialized immune cells generated in vivo reduce cardiac scar tissue in mice, a new study shows.
Antibodies in breastmilk from SARS-CoV-2 infection or mRNA vaccination neutralize the virus.
Antibodies Against SARS-CoV-2 in Breast Milk Differ Between Vaccinated and Infected Mothers
Roni Dengler, PhD | Dec 6, 2021 | 3 min read
All antibodies against SARS-CoV-2 found in breast milk neutralized the virus.
black-legged deer tick waits on leaf for host to feed on
A Lab-Stage mRNA Vaccine Targeting Ticks May Offer Protection Against Lyme and Other Tick-Borne Diseases
Andaleeb Sajid | Nov 18, 2021 | 3 min read
NIH researcher Andaleeb Sajid discusses her study’s finding that ticks were unable to feed on vaccinated guinea pigs, preventing transmission of the pathogen that causes Lyme disease.
istock image 800x560
Can mRNA Vaccine Momentum Propel Tumor Immunotherapies?
Aparna Nathan, PhD | Nov 12, 2021 | 4 min read
A guide to mRNA-based cancer vaccines and where they’re headed next
cartoon image showing colorful collection of syringes, coronavirus particles, and mrna to represent the vaccine development
Optogenetics and mRNA Vaccines Net Lasker Awards
Annie Melchor | Sep 24, 2021 | 2 min read
This year’s winners are Dieter Oesterhelt, Peter Hegemann, Karl Deisseroth, Drew Weissman, Katalin Karikó, and David Baltimore.
moderna and pfizer vaccine vials
Moderna vs. Pfizer: Is There a “Best” mRNA Vaccine?
Alejandra Manjarrez, PhD | Sep 24, 2021 | 10 min read
Both of the mRNA vaccines available in the US are highly effective against severe COVID-19, but recent studies suggest that Moderna’s elicits a stronger immune response and might be better at preventing breakthrough infections.