structural biology
Crystal Structure, Murky Function
Crystal Structure, Murky Function
Ruth Williams | Jan 29, 2015
Scientists have determined the crystal structures of bacterial translocator proteins, but their functions remain unclear.
Mitochondrial Enzyme Detailed
Mitochondrial Enzyme Detailed
Jef Akst | Jan 9, 2015
Researchers reveal clues regarding how an ancient mitochondrial enzyme helps maintain healthy cells across the tree of life.
DNA Bends Control Gene Activation
DNA Bends Control Gene Activation
Kerry Grens | Mar 25, 2014
Genomic structures called i-motifs signal DNA activation, while hairpin loops signal gene suppression.  
Intracellular Spirals
Intracellular Spirals
Kate Yandell | Dec 1, 2013
Membrane twists connect stacked endoplasmic reticulum sheets.
Taking Shape
Taking Shape
Wallace F. Marshall | Dec 1, 2013
The causes of a cell’s three-dimensional structure remain a fundamental mystery of cell biology.
Mental Map
Mental Map
Abdul-Kareem Ahmed | Nov 13, 2013
From determining structures to figuring out functions, brain-mapping scientists are applying new technologies to understand the hub of the central nervous system.
HIV Structural Studies Undermine Prior Work
HIV Structural Studies Undermine Prior Work
Bob Grant | Nov 4, 2013
New research on the structure of the surface protein the virus uses to infiltrate human cells clashes with an earlier paper’s findings, causing some scientists to call for a retraction.
Portrait of an HIV Conspirator
Portrait of an HIV Conspirator
Ed Yong | Sep 12, 2013
The three-dimensional structure of CCR5, a protein which HIV uses to infect humans' cells, could lead to better anti-HIV drugs.
Emily Scott: Enzyme Explorer
Emily Scott: Enzyme Explorer
Dan Cossins | Mar 1, 2013
Associate Professor, Medicinal Chemistry, University of Kansas. Age: 43
Catalyzing Lung Cancer Research
Catalyzing Lung Cancer Research
Dan Cossins | Mar 1, 2013
March 2013 Scientist to Watch Emily Scott explains her work on a lung enzyme that interacts with nicotine and may serve as a drug target.