structural biology
Zooming In on an Antidepressant Target
Zooming In on an Antidepressant Target
Ruth Williams | Apr 6, 2016
Structural studies reveal how SSRI drugs bind to the human serotonin transporter.
Crystal Unclear
Crystal Unclear
Tracy Vence | Oct 15, 2015
A behind-the-scenes look at how researchers solved the high-resolution crystal structure of the nucleosome core particle raises the age-old question of assigning credit in science.
Characterizing DNA Quadruplexes
Characterizing DNA Quadruplexes
Jef Akst | Sep 10, 2015
Researchers are developing new techniques to better understand how and why knots of DNA are distributed throughout the genome.
Neutralizing HIV
Neutralizing HIV
Kerry Grens | Jun 18, 2015
Engineered immunogens based on conserved patches of the virus’s envelope protein point to new strategies for vaccine design.
Spider and Centipede Venom Remarkably Similar
Spider and Centipede Venom Remarkably Similar
Bob Grant | Jun 12, 2015
The predatory toxins employed by animals separated by millions of years of evolution are virtually identical, a study shows.
RNA Stucturomics
RNA Stucturomics
Ruth Williams | Jun 1, 2015
A new high-throughput, transcriptome-wide assay determines RNA structures in vivo.
Renowned Molecular Biologist Dies
Renowned Molecular Biologist Dies
Kerry Grens | May 6, 2015
Alexander Rich, discoverer of Z-DNA, the RNA-DNA double helix, and the structure of collagen, has passed away at age 90.
Crystal Structure, Murky Function
Crystal Structure, Murky Function
Ruth Williams | Jan 29, 2015
Scientists have determined the crystal structures of bacterial translocator proteins, but their functions remain unclear.
Mitochondrial Enzyme Detailed
Mitochondrial Enzyme Detailed
Jef Akst | Jan 9, 2015
Researchers reveal clues regarding how an ancient mitochondrial enzyme helps maintain healthy cells across the tree of life.
DNA Bends Control Gene Activation
DNA Bends Control Gene Activation
Kerry Grens | Mar 25, 2014
Genomic structures called i-motifs signal DNA activation, while hairpin loops signal gene suppression.