Photograph of Humsa Venkatesh
Humsa Venkatesh Probes Cancer’s Grip on the Brain
At Brigham and Women’s Hospital, the cancer biologist is combining research into the tumor microenvironment with the principles of neuroscience to tease apart how cancers grow—and how to stop them.
Humsa Venkatesh Probes Cancer’s Grip on the Brain
Humsa Venkatesh Probes Cancer’s Grip on the Brain

At Brigham and Women’s Hospital, the cancer biologist is combining research into the tumor microenvironment with the principles of neuroscience to tease apart how cancers grow—and how to stop them.

At Brigham and Women’s Hospital, the cancer biologist is combining research into the tumor microenvironment with the principles of neuroscience to tease apart how cancers grow—and how to stop them.

tumor microenvironment
A stained tissue sample of metastatic pancreatic cancer
Tetanus Immunity Protects Mice Against Pancreatic Cancer
Amanda Heidt | Mar 24, 2022
Because most people are vaccinated against tetanus as children, delivering benign bacteria carrying a tetanus antigen into pancreatic tumors makes them visible to memory cells in the immune system, researchers report.
Tumor microbiome composite
Could Cancer’s Microbiome Help Diagnose and Treat the Disease?
Jef Akst | Mar 14, 2022
A growing appreciation of the bacterial assemblages that live within tumors has researchers striving to understand and capitalize on their role.
Overcoming T Cell Therapy Barriers with Engineered Proteins
Overcoming T Cell Therapy Barriers with Engineered Proteins
The Scientist Creative Services Team
Shannon Oda will discuss how to develop novel engineered fusion proteins to improve T cell therapies against hematological and solid tumors.
Illustration showing microbial signatures of cancer in the body
Infographic: Putting Cancer’s Unique Microbiomes to Use
Jef Akst | Mar 14, 2022
From diagnosis to tracking treatment responses, bacteria and other microbes in the blood, gut, and tumors of cancer patients may provide helpful hints for improving their care.
illustration of blue cancer cell extending tendrils around itself
Janus-Faced Neutrophils
Sophie Fessl | Mar 2, 2022
The immune cells facilitate healing, but they may also help tumors metastasize to the lungs after injury, a study in mice finds.
Reinvigorating the Immune System to Attack Cancer Cells Using Highly Specific Antibodies
Reinvigorating the Immune System to Attack Cancer Cells Using Highly Specific Antibodies
Fortis Life Sciences
Cancer immunotherapy targets the tumor microenvironment, blocking the molecular pathways that tumors exploit to prevent immune cell activity.
New Understanding of Metastasis Could Lead to Better Treatments
Shawna Williams | Apr 1, 2021
Recent insights, such as the recognition that disseminated cancer cells can lie dormant for years before seeding secondary tumors, suggest novel strategies for fighting metastatic disease.
CAR Macrophages Tackle Challenges in Solid Cancer Treatment
Amanda Heidt | Mar 26, 2021
Following on the success of CAR T cells used to treat cancers of the blood, researchers have launched a Phase 1 clinical trial of genetically modified macrophages to target solid tumors.
Examine Altered Glycobiology in Cancer
Examining Altered Glycobiology in Cancer
The Scientist Creative Services Team and Vector Laboratories
Changes to protein glycosylation play a major role in dictating cancer progression and prognosis, but could they also present biomarkers or therapeutic targets?
Exploring the Matrix: A Profile of Zena Werb
Diana Kwon | Dec 1, 2019
The cell and molecular biologist unveiled a role for the breakdown of proteins in the extracellular matrix in both healthy and pathogenic cells.
Boosting Immunotherapy Treatments in Mouse Colon Cancer
Jim Daley | Apr 1, 2018
Mice treated with an immunostimulant had better outcomes when researchers blocked the expression of TNFR2, a compound that helps tumors evade immune attack.
How Cancer Circumvents the Immune System
How Cancer Circumvents the Immune System
The Scientist Creative Services Team in collaboration with Bio-Techne
Dario Vignali and Peter Westcott will explore the importance of understanding immune-cancer mechanistic interactions for developing therapeutic approaches.
Macrophages Play a Double Role in Cancer
Amanda B. Keener | Apr 1, 2018
Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.
Image of the Day: Sun Burn
The Scientist Staff and The Scientist Staff | Oct 20, 2017
When certain melanocyte stem cells are exposed to UV rays, a molecular cascade can trigger melanoma, scientists find in mice.
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A 3-D Tumor Microenvironment for Personalized Immunotherapy
Roni Dengler, PhD
A new platform enables screening a wide range of combination anticancer therapeutics in a matter of days, which may translate to personalized therapeutic regimens for patients in less time.
Cancer and Its Milieu
The Scientist Staff | Mar 31, 2017
Lawrence Berkeley National Laboratory researcher and April profilee Mina Bissell explains the intricacies of how cancer takes hold in a body.
Cancer's Vanguard
Catherine Offord | Apr 1, 2016
Exosomes are emerging as key players in metastasis.
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A New Model with Fully Functioning Blood Vessels Mimics Brain Cancer
Roni Dengler, PhD
A newly developed platform may one day replace cell culture and animal models to personalize cancer treatment.
The Scientist on the Pulse, April 23
Kerry Grens | Apr 23, 2015
Hot topics in cancer research from the annual meeting of the American Association for Cancer Research