Researchers use a mesenchymal stromal cell-based vector to deliver multiple viruses simultaneously to improve CAR-T cell anti-tumor activity.

In this workshop, learn tips and tricks for preparing cancer tissue samples for a variety of single cell applications.

Katie McKenna discusses a combination CAR T and viral therapy that kills solid tumors.

Katie McKenna will discuss how oncolytic viral therapy enhances CAR-T cell killing of cancer cells.

Following on the success of CAR T cells used to treat cancers of the blood, researchers have launched a Phase 1 clinical trial of genetically modified macrophages to target solid tumors.

The cell and molecular biologist unveiled a role for the breakdown of proteins in the extracellular matrix in both healthy and pathogenic cells.

Mice treated with an immunostimulant had better outcomes when researchers blocked the expression of TNFR2, a compound that helps tumors evade immune attack.

Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.

When certain melanocyte stem cells are exposed to UV rays, a molecular cascade can trigger melanoma, scientists find in mice.

Lawrence Berkeley National Laboratory researcher and April profilee Mina Bissell explains the intricacies of how cancer takes hold in a body.

Exosomes are emerging as key players in metastasis.

Hot topics in cancer research from the annual meeting of the American Association for Cancer Research

Meet some of the people featured in the April 2015 issue of The Scientist.

Cancer treatment becomes more and more personal.

Scientists at this month’s AACR meeting highlighted research on the crucial role of the non-malignant cells that surround tumors in cancer initiation, growth, and response.

A flood of new discoveries has refined our definition of cancer stem cells. Now it’s up to human clinical trials to test if they can make a difference in patients.