New Understanding of Metastasis Could Lead to Better Treatments
New Understanding of Metastasis Could Lead to Better Treatments
Recent insights, such as the recognition that disseminated cancer cells can lie dormant for years before seeding secondary tumors, suggest novel strategies for fighting metastatic disease.
New Understanding of Metastasis Could Lead to Better Treatments
New Understanding of Metastasis Could Lead to Better Treatments

Recent insights, such as the recognition that disseminated cancer cells can lie dormant for years before seeding secondary tumors, suggest novel strategies for fighting metastatic disease.

Recent insights, such as the recognition that disseminated cancer cells can lie dormant for years before seeding secondary tumors, suggest novel strategies for fighting metastatic disease.

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CAR Macrophages Tackle Challenges in Solid Cancer Treatment
CAR Macrophages Tackle Challenges in Solid Cancer Treatment
Amanda Heidt | Mar 26, 2021
Following on the success of CAR T cells used to treat cancers of the blood, researchers have launched a Phase 1 clinical trial of genetically modified macrophages to target solid tumors.
Exploring the Matrix: A Profile of Zena Werb
Exploring the Matrix: A Profile of Zena Werb
Diana Kwon | Dec 1, 2019
The cell and molecular biologist unveiled a role for the breakdown of proteins in the extracellular matrix in both healthy and pathogenic cells.
Boosting Immunotherapy Treatments in Mouse Colon Cancer
Boosting Immunotherapy Treatments in Mouse Colon Cancer
Jim Daley | Apr 1, 2018
Mice treated with an immunostimulant had better outcomes when researchers blocked the expression of TNFR2, a compound that helps tumors evade immune attack.
Macrophages Play a Double Role in Cancer
Macrophages Play a Double Role in Cancer
Amanda B. Keener | Apr 1, 2018
Macrophages play numerous roles within tumors, leaving cancer researchers with a choice: eliminate the cells or recruit them.
Image of the Day: Sun Burn
Image of the Day: Sun Burn
The Scientist Staff, The Scientist Staff | Oct 20, 2017
When certain melanocyte stem cells are exposed to UV rays, a molecular cascade can trigger melanoma, scientists find in mice.
Cancer and Its Milieu
Cancer and Its Milieu
The Scientist Staff | Mar 31, 2017
Lawrence Berkeley National Laboratory researcher and April profilee Mina Bissell explains the intricacies of how cancer takes hold in a body.
Cancer's Vanguard
Cancer's Vanguard
Catherine Offord | Apr 1, 2016
Exosomes are emerging as key players in metastasis.
<em>The Scientist</em> on the Pulse, April 23
The Scientist on the Pulse, April 23
Kerry Grens | Apr 23, 2015
Hot topics in cancer research from the annual meeting of the American Association for Cancer Research
To Each His Own
To Each His Own
Mary Beth Aberlin | Apr 1, 2015
Cancer treatment becomes more and more personal.
Contributors
Contributors
Jenny Rood | Apr 1, 2015
Meet some of the people featured in the April 2015 issue of The Scientist.
Exploring the Tumor Neighborhood
Exploring the Tumor Neighborhood
Dan Cossins | Apr 10, 2013
Scientists at this month’s AACR meeting highlighted research on the crucial role of the non-malignant cells that surround tumors in cancer initiation, growth, and response.
Are Cancer Stem Cells Ready for Prime Time?
Are Cancer Stem Cells Ready for Prime Time?
Suling Liu, Hasan Korkaya, and Max S. Wicha | Apr 1, 2012
A flood of new discoveries has refined our definition of cancer stem cells. Now it’s up to human clinical trials to test if they can make a difference in patients.