Clocking Epigenetics

DNA methylation status can predict age in various human tissues, a study shows.

abby olena
| 2 min read

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Update (May 15, 2015): Genome Biology has published an erratum to the article discussed here. From author Steve Horvath: “I recently described an epigenetic biomarker of aging based on DNA methylation levels. Unfortunately, I made a software coding error in my analysis of the cancer data, but not of the non-cancer tissue data. The error effectively added an offset term to the age estimates. All of my results from that involve non-cancerous tissue or cancer cell lines remain valid but I have to report some corrections for the cancer tissue data. In particular, I have to retract the statement that cancer is associated with an increased DNA methylation age (i.e. positive age acceleration) in most cancer types. In fact, while some cancer types show positive ...

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Meet the Author

  • abby olena

    Abby Olena, PhD

    As a freelancer for The Scientist, Abby reports on new developments in life science for the website.
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