Deep Brain Stimulation Improves Depression Symptoms: Study

The effects of the therapy in a small group of  patients were long-lasting, researchers say, adding to evidence that the approach works for treatment-resistant depression.

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Deep brain stimulation can durably improve depression symptoms in people who don’t respond well to other treatments, according to a small study published last week (October 4) in The American Journal of Psychiatry. The findings, based on up to eight years of data from 28 people wearing brain-stimulating implants, showed that most people receiving the therapy responded well and maintained their improvements over time.

“The bottom line is that if you get better, you stay better,” study coauthor Helen Mayberg, a neurologist at the Icahn School of Medicine at Mount Sinai who holds a share of an intellectual property patent on the therapy, tells The New York Times. “You don’t lose the effects over time. You wear the device like a pacemaker, and you stay well.”

Deep brain stimulation, or DBS, involves implanting a small neurostimulator into a patient’s brain to send out electrical impulses to ...

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