Deep Brain Stimulation Improves Depression Symptoms: Study

The effects of the therapy in a small group of  patients were long-lasting, researchers say, adding to evidence that the approach works for treatment-resistant depression.

| 2 min read

Register for free to listen to this article
Listen with Speechify
0:00
2:00
Share

ABOVE: © ISTOCK.COM, WHITEHOUNE

Deep brain stimulation can durably improve depression symptoms in people who don’t respond well to other treatments, according to a small study published last week (October 4) in The American Journal of Psychiatry. The findings, based on up to eight years of data from 28 people wearing brain-stimulating implants, showed that most people receiving the therapy responded well and maintained their improvements over time.

“The bottom line is that if you get better, you stay better,” study coauthor Helen Mayberg, a neurologist at the Icahn School of Medicine at Mount Sinai who holds a share of an intellectual property patent on the therapy, tells The New York Times. “You don’t lose the effects over time. You wear the device like a pacemaker, and you stay well.”

Deep brain stimulation, or DBS, involves implanting a small neurostimulator into a patient’s brain to send out electrical impulses to ...

Interested in reading more?

Become a Member of

The Scientist Logo
Receive full access to more than 35 years of archives, as well as TS Digest, digital editions of The Scientist, feature stories, and much more!
Already a member? Login Here
May digest 2025 cover
May 2025, Issue 1

Study Confirms Safety of Genetically Modified T Cells

A long-term study of nearly 800 patients demonstrated a strong safety profile for T cells engineered with viral vectors.

View this Issue
iStock

TaqMan Probe & Assays: Unveil What's Possible Together

Thermo Fisher Logo
Meet Aunty and Tackle Protein Stability Questions in Research and Development

Meet Aunty and Tackle Protein Stability Questions in Research and Development

Unchained Labs
Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Detecting Residual Cell Line-Derived DNA with Droplet Digital PCR

Bio-Rad
How technology makes PCR instruments easier to use.

Making Real-Time PCR More Straightforward

Thermo Fisher Logo

Products

fujirebio-square-logo

Fujirebio Receives Marketing Clearance for Lumipulse® G pTau 217/ β-Amyloid 1-42 Plasma Ratio In-Vitro Diagnostic Test

The Scientist Placeholder Image

Biotium Launches New Phalloidin Conjugates with Extended F-actin Staining Stability for Greater Imaging Flexibility

Leica Microsystems Logo

Latest AI software simplifies image analysis and speeds up insights for scientists

BioSkryb Genomics Logo

BioSkryb Genomics and Tecan introduce a single-cell multiomics workflow for sequencing-ready libraries in under ten hours